Second iatrogenic CJD case confirmed Korea

Second iCJD case confirmed


Date 2011-12-09 Hit

25





Second iCJD case confirmed




- Investigation is planned for all CJD patients that can be traced to check whether they have received a dura mater graft, etc -







Korea Centers for Disease Control and Prevention (KCDC; Director Jun, Byung Yool) informed that an additional case of iCJD has been confirmed in a patient who was earlier reported to have been infected with sporadic CJD (sCJD) through the study of the patient’s medical history. This iCJD seems to have occurred after the transplant of the dura mater graft.







The patient in the case is a 48-year-old man who was diagnosed with sCJD in Jul. 2011 at a hospital located in the metropolitan area and his case was reported through the legal communicable disease reporting system. According to this man’s medical record, he got a surgery for intracranial hemorrhage caused by an external injury in May 1988 and received a transplant of the “Lyodura” dura mater.






Generally, it is very rare to carry out a transplant of the dura mater in the surgery for intracranial hemorrhage and the manufacturing history of the dura mater used in the transplantation in this case couldn’t be found.







KCDC has requested the Korean Neurological Association, the Korean Medical Association, and the Korean Hospital Association, etc to keep detailed records of medical histories related to iCJD including operation histories of the patients suspected of having sCJD.







KCDC also said that it would conduct a tracking investigation to check and confirm the possibility of exposure to the risk of iCJD infections by all the CJD patients that can be traced with medical records at hospitals of all levels including the CJD patients that have been reported through the legal communicable disease reporting system since 2000.






http://english.mw.go.kr/front_eng/al/sal0201vw.jsp?PAR_MENU_ID=1002&MENU_ID=100203&page=1&CONT_SEQ=261181&SEARCHKEY=&SEARCHVALUE=





Press Release

Date
8 Dec. / (2 pages)
Division
Telephone

Manager/POC
Park, Hye Kyung/Huh, Chang Ho
Division of Infectious Disease Control
043-719-7120

043-719-7116









Second iCJD case confirmed







- Investigation is planned for all CJD patients that can be traced to check whether they have received a dura mater graft, etc


-

□ Korea Centers for Disease Control and Prevention (KCDC; Director Jun, Byung Yool) informed that an additional case of iCJD has been confirmed in a patient who was earlier reported to have been infected with sporadic CJD (sCJD) through the study of the patient’s medical history. This iCJD seems to have occurred after the transplant of the dura mater graft.

□ The patient in the case is a 48-year-old man who was diagnosed with sCJD in Jul. 2011 at a hospital located in the metropolitan area and his case was reported through the legal communicable disease reporting system. According to this man’s medical record, he got a surgery for intracranial hemorrhage caused by an external injury in May 1988 and received a transplant of the “Lyodura” dura mater.



○ Generally, it is very rare to carry out a transplant of the dura mater in the surgery for intracranial hemorrhage and the manufacturing history of the dura mater used in the transplantation in this case couldn’t be found.



□ KCDC has requested the Korean Neurological Association, the Korean Medical Association, and the Korean Hospital Association, etc to keep detailed records of medical histories related to iCJD including operation histories of the patients suspected of having sCJD.




□ KCDC also said that it would conduct a tracking investigation to check and confirm the possibility of exposure to the risk of iCJD infections by all the CJD patients that can be traced with medical records at hospitals of all levels including the CJD patients that have been reported through the legal communicable disease reporting system since 2000.




iCJD-tracking investigation plan (draft)





[Attachment]





http://download.mw.go.kr/front/modules/download.jsp?BOARD_ID=1365&CONT_SEQ=261181&FILE_SEQ=78227&FILE_NAME=[ENG][12.8.FRI] second case of iCJD confirmed.docx




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Thursday, December 08, 2011

A case of Iatrogenic Creutzfeldt Jakob Disease (iCJD) in a patient who had received a German-manufactured human dura mater graft 23 years ago


http://creutzfeldt-jakob-disease.blogspot.com/2011/12/case-of-iatrogenic-creutzfeldt-jakob.html




Thursday, December 8, 2011

S. Korea confirms second case of iatrogenic Creutzfeldt-Jakob disease 48-year-old man

2011/12/08 11:08 KST


http://usdavskorea.blogspot.com/2011/12/s-korea-confirms-second-case-of.html




Wednesday, November 30, 2011


First iCJD Death Confirmed in Korea


http://creutzfeldt-jakob-disease.blogspot.com/2011/11/first-icjd-death-confirmed-in-korea.html



http://usdavskorea.blogspot.com/




Saturday, June 25, 2011



Transmissibility of BSE-L and Cattle-Adapted TME Prion Strain to Cynomolgus Macaque



"BSE-L in North America may have existed for decades"



http://transmissiblespongiformencephalopathy.blogspot.com/2011/06/transmissibility-of-bse-l-and-cattle.html




http://transmissiblespongiformencephalopathy.blogspot.com/



http://creutzfeldt-jakob-disease.blogspot.com/



http://bseusa.blogspot.com/



http://bse-atypical.blogspot.com/



http://madcowusda.blogspot.com/



http://chronic-wasting-disease.blogspot.com/



http://nor-98.blogspot.com/



http://scrapie-usa.blogspot.com/








TSS

Creutzfeldt-Jakob Disease in Recipients of Corneal Transplants

Creutzfeldt-Jakob Disease in Recipients of Corneal Transplants.

Case Report

Cornea. 27(7):851-854, August 2008. Maddox, Ryan A MPH *; Belay, Ermias D MD *; Curns, Aaron T MPH +; Zou, Wen-Quan MD, PhD ++; Nowicki, Scott MPH [S]; Lembach, Richard G MD [P]; Geschwind, Michael D MD, PhD **; Haman, Aissa MD **; Shinozaki, Naoshi ++; Nakamura, Yosikazu MD ++++; Borer, Mark J CEBT [S][S]; Schonberger, Lawrence B MD * Abstract: Purpose: Creutzfeldt-Jakob disease (CJD) transmission has been documented to occur from the use of corneal grafts. We report 4 cases of CJD with a history of corneal transplantation and assess the frequency of coincidental CJD among corneal transplant recipients.

Methods: Medical records and eye bank documents were reviewed. Genetic and neuropathologic tests on available specimens were performed at the National Prion Disease Pathology Surveillance Center. Statistical analyses were used to determine the expected number of coincidental CJD cases among the US population with a history of corneal transplantation.

Results: Four CJD decedents with histories of corneal transplantation were identified: 3 from the United States and 1 from Japan. The time from transplant to onset of CJD symptoms ranged from 2 years, 11 months to 18 years. Available eye bank records did not suggest evidence of neurologic illness in the donors. Using corneal transplantation and CJD death data from 1990 through 2006, statistical analyses suggest that a case of coincidental sporadic CJD will occur among the population of corneal transplant recipients approximately every 1.5 years.

Conclusions: It is likely that these 4 recipients of transplanted corneas had sporadic CJD. Because of the many corneal transplantations performed each year in the United States, occasional cases of sporadic CJD in this population are expected.

(C) 2008 Lippincott Williams & Wilkins, Inc.


http://www.corneajrnl.com/pt/re/cornea/abstract.00003226-200808000-00021.htm;jsessionid=LL1QFs6NXh3P3P29QFYTJJsQ34sLm59pnnT4DQ1sNRBhMLMyJ561!1629792715!181195629!8091!-1


> Because of the many corneal transplantations performed each year in the United States, occasional cases of sporadic CJD in this population are expected.


gee wiz, i feel much better, and i am sure any recipient of a cornea will too. ...not. ...TSS



CJD, they eye's have it and they could be stealing them from your loved one

http://www.mad-cow.org/dec99_news.html#bbb


Subject: RE-The Eyes Have It (cjd) and they could be stealing them from your loved one... "pay back time" Date: Sat, 16 Sep 2000 10:04:26 -0700 From: "Terry S. Singeltary Sr." Reply-To: Bovine Spongiform Encephalopathy To: BSE-L@uni-karlsruhe.de

######### Bovine Spongiform Encephalopathy #########

Greetings List Members,

I hate to keep kicking a madcow, but this still is very disturbing to me. Not only for the recipient of the cornea's, but as well, for the people whom would be operated on, using the same tools that were used to put those stolen cornea's in the recipient with. ...

snip...see full text ;


Saturday, January 26, 2008
CJD HGH BODY SNATCHERS

http://creutzfeldt-jakob-disease.blogspot.com/2008/01/cjd-hgh-body-snatchers.html


Thursday, July 24, 2008
Prion diseases are efficiently transmitted by blood transfusion in sheep
Submitted April 18, 2008 Accepted June 28, 2008

http://vcjdblood.blogspot.com/2008/07/prion-diseases-are-efficiently.html

vCJD questionnaire

http://www.bseinquiry.gov.uk/report/volume8/pdf/1stquestionnaire.pdf


USA WRITTEN CJD QUESTIONNAIRE ???

http://cjdquestionnaire.blogspot.com/


why is a cjd questionnaire not listed on the cjd foundation 'forms' site with the rest of their forms ???

i thought they had one now going out to all families of victims of a human TSE???

this is very important that a _written_ cjd questionnaire, asking extensive questions pertaining to any potential route and source of the TSE agent be submitted to every family of a victim of a human TSE. this is key to finding cause. so why is this still so difficult? are the families of CJD victims getting these written cjd questionnaires??? i hope so....

2008 The statistical incidence of CJD cases in the United States has been revised to reflect that there is

_one case per 9000 in adults age 55 and older_.

Eighty-five percent of the cases are sporadic, meaning there is no known cause at present.

http://www.cjdfoundation.org/fact.html


FDA FAILED US

http://fdafailedus.blogspot.com/


SCIENCE BUSHWHACKED

http://sciencebushwhacked.blogspot.com/


Sunday, July 20, 2008 Red Cross told to fix blood collection or face charges 15 years after warnings issued, few changes made to ensure safety

http://vcjdblood.blogspot.com/2008/07/red-cross-told-to-fix-blood-collection.html



TSS