Mad cow disease experts at UC Davis want to discuss claims of TWO HUMAN CASES RECENTLY
From: Terry S. Singeltary Sr.
Sent: Friday, February 10, 2012 11:53 AM
To: CJD-L
Cc: rebreitmeyer@ucdavis.edu ; csigurdson@ucsd.edu ; pjbailey@ucdavis.edu ; tlehenbauer@ucdavis.edu ; jscullor@ucdavis.edu ; jmaas@ucdavis.edu ; CJDVOICE CJDVOICE ; bloodcjd bloodcjd ; aabney@sfchronicle.com ; waddiego@sfchronicle.com ; eallday@sfchronicle.com ; pbronstein@sfchronicle.com ; wbushee@sfchronicle.com ; eallday@sfchronicle.com ; opinion@marinij.com ; rhalstead@marinij.com
Subject: Mad cow disease experts at UC Davis spread BSe to California
more BSe (same old song and dance$$$) from some of our mad cow officials prion gods here ;
Mad cow disease experts at UC Davis
February 10, 2012
Two Northern California residents were recently diagnosed as having a type of Creutzfeldt-Jakob disease that is sometimes associated with mad cow disease, or bovine spongiform encephalopathy (BSE). The following UC Davis experts are available to answer questions about mad cow and associated diseases.
http://www.news.ucdavis.edu/search/news_detail.lasso?id=10146
I bet if you contact these folks, they will tell you, mad cow is not in the USA, except for one case from Canada. they may or may not mention the other two _documented_ atypical mad cows, and or the other mad cows that were covered up, like the one in Texas. or, I doubt that they will tell you that science has shown a link to sporadic CJD from atypical BSE, and or atypical Scrapie, and both have been documented in North America.
Then ask them how they are protecting the medical and surgical, blood and tissue donations, ask them how those are being protected. I am sure they will lay claim to the CJD surveillance, which we all know has failed as bad as the BSE surveillance and testing program? nope, I doubt any of these prion gods will mention this. or the science that is showing that indeed CWD may be a zoonosis disease, and a risk factor to humans. nope, did not see any of this on their webpage, why is this ??? it’s all 3 decade old science, i.e. the UKBSEnvCJD only theory still in 2012. ...God Help Us !
how about a little recent science to brighten the day..........nay, the government would rather use 3 decade old science, and put on a song and dance show full of BSe. ...and the media follows through as usual
God save the cattle industry at all cost $$$ including human life. ...
ignore sound science at your own peril...
Thursday, August 12, 2010
Seven main threats for the future linked to prions
First threat
The TSE road map defining the evolution of European policy for protection against prion diseases is based on a certain numbers of hypotheses some of which may turn out to be erroneous. In particular, a form of BSE (called atypical Bovine Spongiform Encephalopathy), recently identified by systematic testing in aged cattle without clinical signs, may be the origin of classical BSE and thus potentially constitute a reservoir, which may be impossible to eradicate if a sporadic origin is confirmed.
***Also, a link is suspected between atypical BSE and some apparently sporadic cases of Creutzfeldt-Jakob disease in humans. These atypical BSE cases constitute an unforeseen first threat that could sharply modify the European approach to prion diseases.
Second threat
snip...
http://www.neuroprion.org/en/np-neuroprion.html
Rural and Regional Affairs and Transport References Committee
The possible impacts and consequences for public health, trade and agriculture of the Government's decision to relax import restrictions on beef Final report June 2010
2.65 At its hearing on 14 May 2010, the committee heard evidence from Dr Alan Fahey who has recently submitted a thesis on the clinical neuropsychiatric, epidemiological and diagnostic features of Creutzfeldt-Jakob disease.48 Dr Fahey told the committee of his concerns regarding the lengthy incubation period for transmissible spongiform encephalopathies, the inadequacy of current tests and the limited nature of our current understanding of this group of diseases.49
2.66 Dr Fahey also told the committee that in the last two years a link has been established between forms of atypical CJD and atypical BSE. Dr Fahey said that: They now believe that those atypical BSEs overseas are in fact causing sporadic Creutzfeldt-Jakob disease. They were not sure if it was due to mad sheep disease or a different form. If you look in the textbooks it looks like this is just arising by itself. But in my research I have a summary of a document which states that there has never been any proof that sporadic Creutzfeldt-Jakob disease has arisen de novo-has arisen of itself. There is no proof of that. The recent research is that in fact it is due to atypical forms of mad cow disease which have been found across Europe, have been found in America and have been found in Asia. These atypical forms of mad cow disease typically have even longer incubation periods than the classical mad cow disease.50
http://www.aph.gov.au/senate/committee/rrat_ctte/mad_cows/report/report.pdf
Wednesday, March 31, 2010
Atypical BSE in Cattle
To date the OIE/WAHO assumes that the human and animal health standards set out in the BSE chapter for classical BSE (C-Type) applies to all forms of BSE which include the H-type and L-type atypical forms. This assumption is scientifically not completely justified and accumulating evidence suggests that this may in fact not be the case. Molecular characterization and the spatial distribution pattern of histopathologic lesions and immunohistochemistry (IHC) signals are used to identify and characterize atypical BSE. Both the L-type and H-type atypical cases display significant differences in the conformation and spatial accumulation of the disease associated prion protein (PrPSc) in brains of afflicted cattle. Transmission studies in bovine transgenic and wild type mouse models support that the atypical BSE types might be unique strains because they have different incubation times and lesion profiles when compared to C-type BSE. When L-type BSE was inoculated into ovine transgenic mice and Syrian hamster the resulting molecular fingerprint had changed, either in the first or a subsequent passage, from L-type into C-type BSE.
In addition, non-human primates are specifically susceptible for atypical BSE as demonstrated by an approximately 50% shortened incubation time for L-type BSE as compared to C-type. Considering the current scientific information available, it cannot be assumed that these different BSE types pose the same human health risks as C-type BSE or that these risks are mitigated by the same protective measures.
This study will contribute to a correct definition of specified risk material (SRM) in atypical BSE. The incumbent of this position will develop new and transfer existing, ultra-sensitive methods for the detection of atypical BSE in tissue of experimentally infected cattle.
http://www.prionetcanada.ca/detail.aspx?menu=5&dt=293380&app=93&cat1=387&tp=20&lk=no&cat2
2010-2011
When L-type BSE was inoculated into ovine transgenic mice and Syrian hamster the resulting molecular fingerprint had changed, either in the first or a subsequent passage, from L-type into C-type BSE. In addition, non-human primates are specifically susceptible for atypical BSE as demonstrated by an approximately 50% shortened incubation time for L-type BSE as compared to C-type. Considering the current scientific information available, it cannot be assumed that these different BSE types pose the same human health risks as C-type BSE or that these risks are mitigated by the same protective measures. This study will contribute to a correct definition of specified risk material (SRM) in atypical BSE. The incumbent of this position will develop new and transfer existing, ultra-sensitive methods for the detection of atypical BSE in tissue of experimentally infected cattle.
http://www.prionetcanada.ca/detail.aspx?menu=5&dt=293380&app=93&cat1=387&tp=20&lk=no&cat2
Saturday, June 25, 2011
Transmissibility of BSE-L and Cattle-Adapted TME Prion Strain to Cynomolgus Macaque
"BSE-L in North America may have existed for decades"
http://transmissiblespongiformencephalopathy.blogspot.com/2011/06/transmissibility-of-bse-l-and-cattle.html
Over the next 8-10 weeks, approximately 40% of all the adult mink on the farm died from TME.
snip...
The rancher was a ''dead stock'' feeder using mostly (>95%) downer or dead dairy cattle...
http://web.archive.org/web/20030516051623/http://www.bseinquiry.gov.uk/files/mb/m09/tab05.pdf
SEE FULL TEXT AND MORE HERE ;
Saturday, March 5, 2011
MAD COW ATYPICAL CJD PRION TSE CASES WITH CLASSIFICATIONS PENDING ON THE RISE IN NORTH AMERICA
http://transmissiblespongiformencephalopathy.blogspot.com/2011/03/mad-cow-atypical-cjd-prion-tse-cases.html
Thursday, January 26, 2012
The Risk of Prion Zoonoses
Science 27 January 2012: Vol. 335 no. 6067 pp. 411-413 DOI: 10.1126/science.1218167
http://transmissiblespongiformencephalopathy.blogspot.com/2012/01/risk-of-prion-zoonoses.html
Thursday, January 26, 2012
Facilitated Cross-Species Transmission of Prions in Extraneural Tissue
Science 27 January 2012: Vol. 335 no. 6067 pp. 472-475 DOI: 10.1126/science.1215659
snip...
Our data call for closer examination of extraneural PrPres in humanized or primate models when assessing any zoonotic potential of animal prions. The human species barrier to BSE prions may be dramatically lower than previously anticipated, according to brain PrPres detection only (10, 24, 25, 32). Because the oral route is known to target lymphoid tissue, albeit less well than the intracerebral route used here (15), our data reinforce the legitimacy of the current investigations aimed at evaluating the proportion of silent carriers (26, 33, 34) in the BSE-exposed UK population (35). To provide a reliable assessment of people at risk and determining the probability of vCJD onward transmission via surgery or donated blood or organs, it may be necessary to pursue such screening policy on a long-term basis, because, as shown here, prions could persist silently for nearly a third of a host’s life span before being detectable extraneurally by conventional diagnostic methods. Finally, including prion detection in the lymphoid tissue whenever possible might be considered for the surveillance of people exposed to CWD-infected tissue.
Supporting Online Material
www.sciencemag.org/cgi/content/full/335/6067/472/DC1
snip...see full text and more here ;
http://transmissiblespongiformencephalopathy.blogspot.com/2012/01/facilitated-cross-species-transmission.html
Transmissible Spongiform encephalopathy (TSE) animal and human TSE in North America
14th ICID International Scientific Exchange Brochure -
Final Abstract Number: ISE.114
Session: International Scientific Exchange
Transmissible Spongiform encephalopathy (TSE) animal and human TSE in North America
update October 2009
T. Singeltary
Bacliff, TX, USA
Background:
An update on atypical BSE and other TSE in North America. Please remember, the typical U.K. c-BSE, the atypical l-BSE (BASE), and h-BSE have all been documented in North America, along with the typical scrapie's, and atypical Nor-98 Scrapie, and to date, 2 different strains of CWD, and also TME. All these TSE in different species have been rendered and fed to food producing animals for humans and animals in North America (TSE in cats and dogs ?), and that the trading of these TSEs via animals and products via the USA and Canada has been immense over the years, decades.
Methods:
12 years independent research of available data
Results:
I propose that the current diagnostic criteria for human TSEs only enhances and helps the spreading of human TSE from the continued belief of the UKBSEnvCJD only theory in 2009. With all the science to date refuting it, to continue to validate this old myth, will only spread this TSE agent through a multitude of potential routes and sources i.e. consumption, medical i.e., surgical, blood, dental, endoscopy, optical, nutritional supplements, cosmetics etc.
Conclusion:
I would like to submit a review of past CJD surveillance in the USA, and the urgent need to make all human TSE in the USA a reportable disease, in every state, of every age group, and to make this mandatory immediately without further delay. The ramifications of not doing so will only allow this agent to spread further in the medical, dental, surgical arena's. Restricting the reporting of CJD and or any human TSE is NOT scientific. Iatrogenic CJD knows NO age group, TSE knows no boundaries. I propose as with Aguzzi, Asante, Collinge, Caughey, Deslys, Dormont, Gibbs, Gajdusek, Ironside, Manuelidis, Marsh, et al and many more, that the world of TSE Transmissible Spongiform Encephalopathy is far from an exact science, but there is enough proven science to date that this myth should be put to rest once and for all, and that we move forward with a new classification for human and animal TSE that would properly identify the infected species, the source species, and then the route.
page 114 ;
http://ww2.isid.org/Downloads/14th_ICID_ISE_Abstracts.pdf
and yes, the USDA et al are still feeding cows to cows.........they never stopped...............see ;
Sunday, February 5, 2012
February 2012 Update on Feed Enforcement Activities to Limit the Spread of BSE
http://transmissiblespongiformencephalopathy.blogspot.com/2012/02/february-2012-update-on-feed.html
http://chronic-wasting-disease.blogspot.com/
http://creutzfeldt-jakob-disease.blogspot.com/
http://transmissiblespongiformencephalopathy.blogspot.com/
Terry S. Singeltary Sr. on the Creutzfeldt-Jakob Disease Public Health Crisis
http://www.youtube.com/watch?v=zf3lfz9NrT4
http://www.youtube.com/watch?v=c0tWkNvhO4g
http://www.youtube.com/watch?v=zf3lfz9NrT4&feature=results_main&playnext=1&list=PL780BE2AF0B62A944
full text with source references ;
http://transmissiblespongiformencephalopathy.blogspot.com/2011/08/terry-singeltary-sr-on-creutzfeldt.html
Thursday, February 09, 2012
Colorado Farm-Raised Deer Farms and CWD there from 2012 report Singeltary et al
http://chronic-wasting-disease.blogspot.com/2012/02/colorado-farm-raised-deer-farms-and-cwd.html
Thursday, February 09, 2012
50 GAME FARMS IN USA INFECTED WITH CHRONIC WASTING DISEASE
http://chronic-wasting-disease.blogspot.com/2012/02/50-game-farms-to-date-in-usa-infected.html
Thursday, February 09, 2012
THREE KANSAS DEER CONFIRMED POSITIVE IN EARLY STAGES OF CWD TESTING
http://chronic-wasting-disease.blogspot.com/2012/02/three-kansas-deer-confirmed-positive-in.html
Sunday, January 22, 2012
Chronic Wasting Disease CWD cervids interspecies transmission
http://chronic-wasting-disease.blogspot.com/2012/01/chronic-wasting-disease-cwd-cervids.html
Wednesday, February 1, 2012
CJD and PLASMA / URINE PRODUCTS EMA Position Statements Alberto Ganan Jimenez, European Medicines Agency PDA TSE Safety Forum, 30 June 2011
http://transmissiblespongiformencephalopathy.blogspot.com/2012/02/cjd-and-plasma-urine-products-ema.html
PIG IN A POKE...
this is what happens when you ignore decades old sound science, and replace it with political junk science $$$ on BSE aka mad cow type disease i.e. TSE Prion disease, just to save the industry $$$
Sunday, January 29, 2012
Prion Disease Risks in the 21st Century 2011 PDA European Virus-TSE Safety Dr. Detwiler
Dr. Detwiler published Prion Disease Risks in the 21st Century 2011 PDA European Virus-TSE Safety Forum\Presentations TSE\ Page 33 and 34 of 44 ;
http://www.pda.org/
http://transmissiblespongiformencephalopathy.blogspot.com/2012/01/prion-disease-risks-in-21st-century.html
Wednesday, January 18, 2012
BSE IN GOATS CAN BE MISTAKEN FOR SCRAPIE
February 1, 2012
http://transmissiblespongiformencephalopathy.blogspot.com/2012/01/bse-in-goats-can-be-mistaken-for.html
Saturday, January 21, 2012
Quick facts about mad cow disease
snip...
NOW, for the rest of the story...
seems this is the typical Governmental spoon fed BSe that most media still use, outdated, and prehistoric science. that’s why were are still in this mess.
sporadic CJD has now been linked to atypical L-BSE and atypical Scrapie.
sporadic CJD has mutated again, and is rising.
L-BSE is more virulent than the typical c-BSE, with an incubation period some 50% shorter.
BOTH atypical L-BSE and atypical Scrapie are documented in North America. why not print that?
CWD in deer and elk spreading, with a second strain emerging. scientist are now very concerned about the potential for CWD to be zoonotic.
why does the media refuse to print this?
why do they not produce these facts for the public?
sadly, it never was about science, it was all about trade $$$
AN update on the TSE prion aka mad cow disease in North America 2012.
Saturday, January 21, 2012
Quick facts about mad cow disease
http://transmissiblespongiformencephalopathy.blogspot.com/2012/01/quick-facts-about-mad-cow-disease.html
Sunday, November 13, 2011
California BSE mad cow beef recall, QFC, CJD, and dead stock downer livestock
http://transmissiblespongiformencephalopathy.blogspot.com/2011/11/california-bse-mad-cow-beef-recall-qfc.html
Friday, December 23, 2011
Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model
Volume 18, Number 1—January 2012 Dispatch
http://transmissiblespongiformencephalopathy.blogspot.com/2011/12/oral-transmission-of-l-type-bovine.html
Monday, December 26, 2011
Prion Uptake in the Gut: Identification of the First Uptake and Replication Sites
http://transmissiblespongiformencephalopathy.blogspot.com/2011/12/prion-uptake-in-gut-identification-of.html
Wednesday, January 11, 2012
Bucks for brains on offer to cattle and sheep producers Queensland TSE PRION TESTING
http://usdameatexport.blogspot.com/2012/01/bucks-for-brains-on-offer-to-cattle-and.html
Monday, January 2, 2012
EFSA Minutes of the 6th Meeting of the EFSA Scientific Network on BSE-TSE Brussels, 29-30 November 2011
http://transmissiblespongiformencephalopathy.blogspot.com/2012/01/efsa-minutes-of-6th-meeting-of-efsa.html
Wednesday, February 1, 2012
Prion Disease Risks in the 21st Century 2011 PDA European Virus-TSE Safety Update on CJD and VCJD Transmission RG Will
http://transmissiblespongiformencephalopathy.blogspot.com/2012/02/prion-disease-risks-in-21st-century.html
Owens, Julie
From: Terry S. Singeltary Sr. [flounder9@verizon.net]
Sent: Monday, July 24, 2006 1:09 PM
To: FSIS RegulationsComments
Subject: [Docket No. FSIS-2006-0011] FSIS Harvard Risk Assessment of Bovine Spongiform Encephalopathy (BSE)
Page 1 of 98
http://www.fsis.usda.gov/OPPDE/Comments/2006-0011/2006-0011-1.pdf
FSIS response to Singeltary et al ;
http://www.fsis.usda.gov/PDF/BSE_Risk_Assess_Response_Public_Comments.pdf
> Ackerman says downed cattle are 50 times more likely to have mad cow disease (also known as Bovine Spongiform Encephalopathy, or BSE) than ambulatory cattle that are suspected of having BSE. Of the 20 confirmed cases of mad cow disease in North America since 1993, at least 16 have involved downer cattle, he said. <
don’t forget the children...
PLEASE be aware, for 4 years, the USDA fed our children all across the Nation (including TEXAS) dead stock downer cows, the most high risk cattle for BSE aka mad cow disease and other dangerous pathogens.
who will watch our children for CJD for the next 5+ decades ???
WAS your child exposed to mad cow disease via the NSLP ???
SCHOOL LUNCH PROGRAM FROM DOWNER CATTLE UPDATE
http://downercattle.blogspot.com/2009/05/who-will-watch-children.html
http://downercattle.blogspot.com/
DID YOUR CHILD CONSUME SOME OF THESE DEAD STOCK DOWNER COWS, THE MOST HIGH RISK FOR MAD COW DISEASE ???
you can check and see here ;
http://www.fns.usda.gov/fns/safety/pdf/Hallmark-Westland_byState.pdf
lost my mom to the Heidenhain Variant of Creutzfeldt Jakob Disease ‘confirmed’ December 14, 1997, and would never accept what the officials told me, ‘it just happens’, ‘no mad cows in USA’, ‘no link to animal TSE prion disease’, etc. all of which have proven to be false, but yet the media continues to print the same old song and dance. ...I made a promise to mom, the truth must be told. all of it !
sorry if I sound angry, because I still am. ...
LAYPERSON
Terry S. Singeltary Sr.
P.O. Box 42
Bacliff, Texas USA 77518
Sent: Friday, February 10, 2012 11:53 AM
To: CJD-L
Cc: rebreitmeyer@ucdavis.edu ; csigurdson@ucsd.edu ; pjbailey@ucdavis.edu ; tlehenbauer@ucdavis.edu ; jscullor@ucdavis.edu ; jmaas@ucdavis.edu ; CJDVOICE CJDVOICE ; bloodcjd bloodcjd ; aabney@sfchronicle.com ; waddiego@sfchronicle.com ; eallday@sfchronicle.com ; pbronstein@sfchronicle.com ; wbushee@sfchronicle.com ; eallday@sfchronicle.com ; opinion@marinij.com ; rhalstead@marinij.com
Subject: Mad cow disease experts at UC Davis spread BSe to California
more BSe (same old song and dance$$$) from some of our mad cow officials prion gods here ;
Mad cow disease experts at UC Davis
February 10, 2012
Two Northern California residents were recently diagnosed as having a type of Creutzfeldt-Jakob disease that is sometimes associated with mad cow disease, or bovine spongiform encephalopathy (BSE). The following UC Davis experts are available to answer questions about mad cow and associated diseases.
http://www.news.ucdavis.edu/search/news_detail.lasso?id=10146
I bet if you contact these folks, they will tell you, mad cow is not in the USA, except for one case from Canada. they may or may not mention the other two _documented_ atypical mad cows, and or the other mad cows that were covered up, like the one in Texas. or, I doubt that they will tell you that science has shown a link to sporadic CJD from atypical BSE, and or atypical Scrapie, and both have been documented in North America.
Then ask them how they are protecting the medical and surgical, blood and tissue donations, ask them how those are being protected. I am sure they will lay claim to the CJD surveillance, which we all know has failed as bad as the BSE surveillance and testing program? nope, I doubt any of these prion gods will mention this. or the science that is showing that indeed CWD may be a zoonosis disease, and a risk factor to humans. nope, did not see any of this on their webpage, why is this ??? it’s all 3 decade old science, i.e. the UKBSEnvCJD only theory still in 2012. ...God Help Us !
how about a little recent science to brighten the day..........nay, the government would rather use 3 decade old science, and put on a song and dance show full of BSe. ...and the media follows through as usual
God save the cattle industry at all cost $$$ including human life. ...
ignore sound science at your own peril...
Thursday, August 12, 2010
Seven main threats for the future linked to prions
First threat
The TSE road map defining the evolution of European policy for protection against prion diseases is based on a certain numbers of hypotheses some of which may turn out to be erroneous. In particular, a form of BSE (called atypical Bovine Spongiform Encephalopathy), recently identified by systematic testing in aged cattle without clinical signs, may be the origin of classical BSE and thus potentially constitute a reservoir, which may be impossible to eradicate if a sporadic origin is confirmed.
***Also, a link is suspected between atypical BSE and some apparently sporadic cases of Creutzfeldt-Jakob disease in humans. These atypical BSE cases constitute an unforeseen first threat that could sharply modify the European approach to prion diseases.
Second threat
snip...
http://www.neuroprion.org/en/np-neuroprion.html
Rural and Regional Affairs and Transport References Committee
The possible impacts and consequences for public health, trade and agriculture of the Government's decision to relax import restrictions on beef Final report June 2010
2.65 At its hearing on 14 May 2010, the committee heard evidence from Dr Alan Fahey who has recently submitted a thesis on the clinical neuropsychiatric, epidemiological and diagnostic features of Creutzfeldt-Jakob disease.48 Dr Fahey told the committee of his concerns regarding the lengthy incubation period for transmissible spongiform encephalopathies, the inadequacy of current tests and the limited nature of our current understanding of this group of diseases.49
2.66 Dr Fahey also told the committee that in the last two years a link has been established between forms of atypical CJD and atypical BSE. Dr Fahey said that: They now believe that those atypical BSEs overseas are in fact causing sporadic Creutzfeldt-Jakob disease. They were not sure if it was due to mad sheep disease or a different form. If you look in the textbooks it looks like this is just arising by itself. But in my research I have a summary of a document which states that there has never been any proof that sporadic Creutzfeldt-Jakob disease has arisen de novo-has arisen of itself. There is no proof of that. The recent research is that in fact it is due to atypical forms of mad cow disease which have been found across Europe, have been found in America and have been found in Asia. These atypical forms of mad cow disease typically have even longer incubation periods than the classical mad cow disease.50
http://www.aph.gov.au/senate/committee/rrat_ctte/mad_cows/report/report.pdf
Wednesday, March 31, 2010
Atypical BSE in Cattle
To date the OIE/WAHO assumes that the human and animal health standards set out in the BSE chapter for classical BSE (C-Type) applies to all forms of BSE which include the H-type and L-type atypical forms. This assumption is scientifically not completely justified and accumulating evidence suggests that this may in fact not be the case. Molecular characterization and the spatial distribution pattern of histopathologic lesions and immunohistochemistry (IHC) signals are used to identify and characterize atypical BSE. Both the L-type and H-type atypical cases display significant differences in the conformation and spatial accumulation of the disease associated prion protein (PrPSc) in brains of afflicted cattle. Transmission studies in bovine transgenic and wild type mouse models support that the atypical BSE types might be unique strains because they have different incubation times and lesion profiles when compared to C-type BSE. When L-type BSE was inoculated into ovine transgenic mice and Syrian hamster the resulting molecular fingerprint had changed, either in the first or a subsequent passage, from L-type into C-type BSE.
In addition, non-human primates are specifically susceptible for atypical BSE as demonstrated by an approximately 50% shortened incubation time for L-type BSE as compared to C-type. Considering the current scientific information available, it cannot be assumed that these different BSE types pose the same human health risks as C-type BSE or that these risks are mitigated by the same protective measures.
This study will contribute to a correct definition of specified risk material (SRM) in atypical BSE. The incumbent of this position will develop new and transfer existing, ultra-sensitive methods for the detection of atypical BSE in tissue of experimentally infected cattle.
http://www.prionetcanada.ca/detail.aspx?menu=5&dt=293380&app=93&cat1=387&tp=20&lk=no&cat2
2010-2011
When L-type BSE was inoculated into ovine transgenic mice and Syrian hamster the resulting molecular fingerprint had changed, either in the first or a subsequent passage, from L-type into C-type BSE. In addition, non-human primates are specifically susceptible for atypical BSE as demonstrated by an approximately 50% shortened incubation time for L-type BSE as compared to C-type. Considering the current scientific information available, it cannot be assumed that these different BSE types pose the same human health risks as C-type BSE or that these risks are mitigated by the same protective measures. This study will contribute to a correct definition of specified risk material (SRM) in atypical BSE. The incumbent of this position will develop new and transfer existing, ultra-sensitive methods for the detection of atypical BSE in tissue of experimentally infected cattle.
http://www.prionetcanada.ca/detail.aspx?menu=5&dt=293380&app=93&cat1=387&tp=20&lk=no&cat2
Saturday, June 25, 2011
Transmissibility of BSE-L and Cattle-Adapted TME Prion Strain to Cynomolgus Macaque
"BSE-L in North America may have existed for decades"
http://transmissiblespongiformencephalopathy.blogspot.com/2011/06/transmissibility-of-bse-l-and-cattle.html
Over the next 8-10 weeks, approximately 40% of all the adult mink on the farm died from TME.
snip...
The rancher was a ''dead stock'' feeder using mostly (>95%) downer or dead dairy cattle...
http://web.archive.org/web/20030516051623/http://www.bseinquiry.gov.uk/files/mb/m09/tab05.pdf
SEE FULL TEXT AND MORE HERE ;
Saturday, March 5, 2011
MAD COW ATYPICAL CJD PRION TSE CASES WITH CLASSIFICATIONS PENDING ON THE RISE IN NORTH AMERICA
http://transmissiblespongiformencephalopathy.blogspot.com/2011/03/mad-cow-atypical-cjd-prion-tse-cases.html
Thursday, January 26, 2012
The Risk of Prion Zoonoses
Science 27 January 2012: Vol. 335 no. 6067 pp. 411-413 DOI: 10.1126/science.1218167
http://transmissiblespongiformencephalopathy.blogspot.com/2012/01/risk-of-prion-zoonoses.html
Thursday, January 26, 2012
Facilitated Cross-Species Transmission of Prions in Extraneural Tissue
Science 27 January 2012: Vol. 335 no. 6067 pp. 472-475 DOI: 10.1126/science.1215659
snip...
Our data call for closer examination of extraneural PrPres in humanized or primate models when assessing any zoonotic potential of animal prions. The human species barrier to BSE prions may be dramatically lower than previously anticipated, according to brain PrPres detection only (10, 24, 25, 32). Because the oral route is known to target lymphoid tissue, albeit less well than the intracerebral route used here (15), our data reinforce the legitimacy of the current investigations aimed at evaluating the proportion of silent carriers (26, 33, 34) in the BSE-exposed UK population (35). To provide a reliable assessment of people at risk and determining the probability of vCJD onward transmission via surgery or donated blood or organs, it may be necessary to pursue such screening policy on a long-term basis, because, as shown here, prions could persist silently for nearly a third of a host’s life span before being detectable extraneurally by conventional diagnostic methods. Finally, including prion detection in the lymphoid tissue whenever possible might be considered for the surveillance of people exposed to CWD-infected tissue.
Supporting Online Material
www.sciencemag.org/cgi/content/full/335/6067/472/DC1
snip...see full text and more here ;
http://transmissiblespongiformencephalopathy.blogspot.com/2012/01/facilitated-cross-species-transmission.html
Transmissible Spongiform encephalopathy (TSE) animal and human TSE in North America
14th ICID International Scientific Exchange Brochure -
Final Abstract Number: ISE.114
Session: International Scientific Exchange
Transmissible Spongiform encephalopathy (TSE) animal and human TSE in North America
update October 2009
T. Singeltary
Bacliff, TX, USA
Background:
An update on atypical BSE and other TSE in North America. Please remember, the typical U.K. c-BSE, the atypical l-BSE (BASE), and h-BSE have all been documented in North America, along with the typical scrapie's, and atypical Nor-98 Scrapie, and to date, 2 different strains of CWD, and also TME. All these TSE in different species have been rendered and fed to food producing animals for humans and animals in North America (TSE in cats and dogs ?), and that the trading of these TSEs via animals and products via the USA and Canada has been immense over the years, decades.
Methods:
12 years independent research of available data
Results:
I propose that the current diagnostic criteria for human TSEs only enhances and helps the spreading of human TSE from the continued belief of the UKBSEnvCJD only theory in 2009. With all the science to date refuting it, to continue to validate this old myth, will only spread this TSE agent through a multitude of potential routes and sources i.e. consumption, medical i.e., surgical, blood, dental, endoscopy, optical, nutritional supplements, cosmetics etc.
Conclusion:
I would like to submit a review of past CJD surveillance in the USA, and the urgent need to make all human TSE in the USA a reportable disease, in every state, of every age group, and to make this mandatory immediately without further delay. The ramifications of not doing so will only allow this agent to spread further in the medical, dental, surgical arena's. Restricting the reporting of CJD and or any human TSE is NOT scientific. Iatrogenic CJD knows NO age group, TSE knows no boundaries. I propose as with Aguzzi, Asante, Collinge, Caughey, Deslys, Dormont, Gibbs, Gajdusek, Ironside, Manuelidis, Marsh, et al and many more, that the world of TSE Transmissible Spongiform Encephalopathy is far from an exact science, but there is enough proven science to date that this myth should be put to rest once and for all, and that we move forward with a new classification for human and animal TSE that would properly identify the infected species, the source species, and then the route.
page 114 ;
http://ww2.isid.org/Downloads/14th_ICID_ISE_Abstracts.pdf
and yes, the USDA et al are still feeding cows to cows.........they never stopped...............see ;
Sunday, February 5, 2012
February 2012 Update on Feed Enforcement Activities to Limit the Spread of BSE
http://transmissiblespongiformencephalopathy.blogspot.com/2012/02/february-2012-update-on-feed.html
http://chronic-wasting-disease.blogspot.com/
http://creutzfeldt-jakob-disease.blogspot.com/
http://transmissiblespongiformencephalopathy.blogspot.com/
Terry S. Singeltary Sr. on the Creutzfeldt-Jakob Disease Public Health Crisis
http://www.youtube.com/watch?v=zf3lfz9NrT4
http://www.youtube.com/watch?v=c0tWkNvhO4g
http://www.youtube.com/watch?v=zf3lfz9NrT4&feature=results_main&playnext=1&list=PL780BE2AF0B62A944
full text with source references ;
http://transmissiblespongiformencephalopathy.blogspot.com/2011/08/terry-singeltary-sr-on-creutzfeldt.html
Thursday, February 09, 2012
Colorado Farm-Raised Deer Farms and CWD there from 2012 report Singeltary et al
http://chronic-wasting-disease.blogspot.com/2012/02/colorado-farm-raised-deer-farms-and-cwd.html
Thursday, February 09, 2012
50 GAME FARMS IN USA INFECTED WITH CHRONIC WASTING DISEASE
http://chronic-wasting-disease.blogspot.com/2012/02/50-game-farms-to-date-in-usa-infected.html
Thursday, February 09, 2012
THREE KANSAS DEER CONFIRMED POSITIVE IN EARLY STAGES OF CWD TESTING
http://chronic-wasting-disease.blogspot.com/2012/02/three-kansas-deer-confirmed-positive-in.html
Sunday, January 22, 2012
Chronic Wasting Disease CWD cervids interspecies transmission
http://chronic-wasting-disease.blogspot.com/2012/01/chronic-wasting-disease-cwd-cervids.html
Wednesday, February 1, 2012
CJD and PLASMA / URINE PRODUCTS EMA Position Statements Alberto Ganan Jimenez, European Medicines Agency PDA TSE Safety Forum, 30 June 2011
http://transmissiblespongiformencephalopathy.blogspot.com/2012/02/cjd-and-plasma-urine-products-ema.html
PIG IN A POKE...
this is what happens when you ignore decades old sound science, and replace it with political junk science $$$ on BSE aka mad cow type disease i.e. TSE Prion disease, just to save the industry $$$
Sunday, January 29, 2012
Prion Disease Risks in the 21st Century 2011 PDA European Virus-TSE Safety Dr. Detwiler
Dr. Detwiler published Prion Disease Risks in the 21st Century 2011 PDA European Virus-TSE Safety Forum\Presentations TSE\ Page 33 and 34 of 44 ;
http://www.pda.org/
http://transmissiblespongiformencephalopathy.blogspot.com/2012/01/prion-disease-risks-in-21st-century.html
Wednesday, January 18, 2012
BSE IN GOATS CAN BE MISTAKEN FOR SCRAPIE
February 1, 2012
http://transmissiblespongiformencephalopathy.blogspot.com/2012/01/bse-in-goats-can-be-mistaken-for.html
Saturday, January 21, 2012
Quick facts about mad cow disease
snip...
NOW, for the rest of the story...
seems this is the typical Governmental spoon fed BSe that most media still use, outdated, and prehistoric science. that’s why were are still in this mess.
sporadic CJD has now been linked to atypical L-BSE and atypical Scrapie.
sporadic CJD has mutated again, and is rising.
L-BSE is more virulent than the typical c-BSE, with an incubation period some 50% shorter.
BOTH atypical L-BSE and atypical Scrapie are documented in North America. why not print that?
CWD in deer and elk spreading, with a second strain emerging. scientist are now very concerned about the potential for CWD to be zoonotic.
why does the media refuse to print this?
why do they not produce these facts for the public?
sadly, it never was about science, it was all about trade $$$
AN update on the TSE prion aka mad cow disease in North America 2012.
Saturday, January 21, 2012
Quick facts about mad cow disease
http://transmissiblespongiformencephalopathy.blogspot.com/2012/01/quick-facts-about-mad-cow-disease.html
Sunday, November 13, 2011
California BSE mad cow beef recall, QFC, CJD, and dead stock downer livestock
http://transmissiblespongiformencephalopathy.blogspot.com/2011/11/california-bse-mad-cow-beef-recall-qfc.html
Friday, December 23, 2011
Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model
Volume 18, Number 1—January 2012 Dispatch
http://transmissiblespongiformencephalopathy.blogspot.com/2011/12/oral-transmission-of-l-type-bovine.html
Monday, December 26, 2011
Prion Uptake in the Gut: Identification of the First Uptake and Replication Sites
http://transmissiblespongiformencephalopathy.blogspot.com/2011/12/prion-uptake-in-gut-identification-of.html
Wednesday, January 11, 2012
Bucks for brains on offer to cattle and sheep producers Queensland TSE PRION TESTING
http://usdameatexport.blogspot.com/2012/01/bucks-for-brains-on-offer-to-cattle-and.html
Monday, January 2, 2012
EFSA Minutes of the 6th Meeting of the EFSA Scientific Network on BSE-TSE Brussels, 29-30 November 2011
http://transmissiblespongiformencephalopathy.blogspot.com/2012/01/efsa-minutes-of-6th-meeting-of-efsa.html
Wednesday, February 1, 2012
Prion Disease Risks in the 21st Century 2011 PDA European Virus-TSE Safety Update on CJD and VCJD Transmission RG Will
http://transmissiblespongiformencephalopathy.blogspot.com/2012/02/prion-disease-risks-in-21st-century.html
Owens, Julie
From: Terry S. Singeltary Sr. [flounder9@verizon.net]
Sent: Monday, July 24, 2006 1:09 PM
To: FSIS RegulationsComments
Subject: [Docket No. FSIS-2006-0011] FSIS Harvard Risk Assessment of Bovine Spongiform Encephalopathy (BSE)
Page 1 of 98
http://www.fsis.usda.gov/OPPDE/Comments/2006-0011/2006-0011-1.pdf
FSIS response to Singeltary et al ;
http://www.fsis.usda.gov/PDF/BSE_Risk_Assess_Response_Public_Comments.pdf
> Ackerman says downed cattle are 50 times more likely to have mad cow disease (also known as Bovine Spongiform Encephalopathy, or BSE) than ambulatory cattle that are suspected of having BSE. Of the 20 confirmed cases of mad cow disease in North America since 1993, at least 16 have involved downer cattle, he said. <
don’t forget the children...
PLEASE be aware, for 4 years, the USDA fed our children all across the Nation (including TEXAS) dead stock downer cows, the most high risk cattle for BSE aka mad cow disease and other dangerous pathogens.
who will watch our children for CJD for the next 5+ decades ???
WAS your child exposed to mad cow disease via the NSLP ???
SCHOOL LUNCH PROGRAM FROM DOWNER CATTLE UPDATE
http://downercattle.blogspot.com/2009/05/who-will-watch-children.html
http://downercattle.blogspot.com/
DID YOUR CHILD CONSUME SOME OF THESE DEAD STOCK DOWNER COWS, THE MOST HIGH RISK FOR MAD COW DISEASE ???
you can check and see here ;
http://www.fns.usda.gov/fns/safety/pdf/Hallmark-Westland_byState.pdf
lost my mom to the Heidenhain Variant of Creutzfeldt Jakob Disease ‘confirmed’ December 14, 1997, and would never accept what the officials told me, ‘it just happens’, ‘no mad cows in USA’, ‘no link to animal TSE prion disease’, etc. all of which have proven to be false, but yet the media continues to print the same old song and dance. ...I made a promise to mom, the truth must be told. all of it !
sorry if I sound angry, because I still am. ...
LAYPERSON
Terry S. Singeltary Sr.
P.O. Box 42
Bacliff, Texas USA 77518
posted by Terry S. Singeltary Sr. at
12:13 PM
