Wednesday, January 29, 2014

Another Suspect case of Creutzfeldt-Jakob disease investigated in Brazil

Suspect case of Creutzfeldt-Jakob disease investigated in Brazil

brain disease Brazil Creutzfeldt-Jakob disease Latin America and the Caribbean prion prion disease transmissible spongiform encephalopathies

The death of a 70-year-old man from Belo Horizonte, Brazil is being investigated by health authorities as possibly being caused by the prion disease, Creutzfeldt-Jakob disease (CJD), according to a Wall Street Journal report Tuesday.

According to the report, tissue samples are currently be analyzed to determine if the cause of death was CJD. Last year, health officials in the city investigated four other suspect cases; however, all tested negative for CJD.

Creutzfeldt-Jakob disease (CJD) is a rare and fatal disease that affects the nervous system and causes deterioration of the brain. It affects about one in a million people each year worldwide. In the United States, only about 200 people are diagnosed with CJD each year.

In the early stages of CJD, the patient may have rapidly failing memory and other cognitive difficulties. These symptoms become worse much faster than with other more common types of dementia, such as Alzheimer’s disease. Other symptoms can include personality changes including anxiety and depression, lack of coordination, and visual disturbances. As the illness progresses, mental deterioration becomes pronounced and involuntary movements such as sudden jerky movements, blindness, weakness of extremities, and coma may occur. There is no treatment or cure.


http://www.theglobaldispatch.com/suspect-case-of-creutzfeldt-jakob-disease-investigated-in-brazil-81276/


>>> health officials in the city investigated four other suspect cases; however, all tested negative for CJD. ...

???

makes you wonder who’s doing the testing, and what test are being used ???

tss



Friday, December 07, 2012

ATYPICAL BSE BRAZIL 2010 FINALLY CONFIRMED OIE 2012

http://bse-atypical.blogspot.com/2012/12/atypical-bse-brazil-2010-finally.html


Wednesday, December 19, 2012


Scientific Report of the European Food Safety Authority on the Assessment of the Geographical BSE Risk (GBR) of Brazil

http://bse-atypical.blogspot.com/2012/12/scientific-report-of-european-food.html


Sunday, December 15, 2013

*** FDA PART 589 -- SUBSTANCES PROHIBITED FROM USE IN ANIMAL FOOD OR FEED VIOLATIONS OFFICIAL ACTION INDICATED OAI UPDATE DECEMBER 2013 UPDATE

http://madcowusda.blogspot.com/2013/12/fda-part-589-substances-prohibited-from.html


Wednesday, January 01, 2014

Molecular Barriers to Zoonotic Transmission of Prions

*** chronic wasting disease, there was no absolute barrier to conversion of the human prion protein.

*** Furthermore, the form of human PrPres produced in this in vitro assay when seeded with CWD, resembles that found in the most common human prion disease, namely sCJD of the MM1 subtype.

http://wwwnc.cdc.gov/eid/article/20/1/13-0858_article.htm

http://chronic-wasting-disease.blogspot.com/2014/01/molecular-barriers-to-zoonotic.html


Subtype 1: (sCJDMM1 and sCJDMV1)

This subtype is observed in patients who are MM homozygous or MV heterozygous at codon 129 of the PrP gene (PRNP) and carry PrPSc Type 1. Clinical duration is short, 3‑4 months.32 The most common presentation in sCJDMM1 patients is cognitive impairment leading to frank dementia, gait or limb ataxia, myoclonic jerks and visual signs leading to cortical blindness (Heidenhain’s syndrome)...

https://www.landesbioscience.com/pdf/06Ahmad_Liberski.pdf


Animals injected with iatrogenic Creutzfeldt–Jakob disease MM1 and genetic Creutzfeldt–Jakob disease MM1 linked to the E200K mutation showed the same phenotypic features as those infected with sporadic Creutzfeldt–Jakob disease MM1 prions...

http://brain.oxfordjournals.org/content/early/2010/09/07/brain.awq234.full.pdf

*** our results raise the possibility that CJD cases classified as VV1 may include cases caused by iatrogenic transmission of sCJD-MM1 prions or food-borne infection by type 1 prions from animals, e.g., chronic wasting disease prions in cervid. In fact, two CJD-VV1 patients who hunted deer or consumed venison have been reported (40, 41). The results of the present study emphasize the need for traceback studies and careful re-examination of the biochemical properties of sCJD-VV1 prions. ***

http://www.jbc.org/cgi/content/abstract/M704597200v1?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext=Cross-sequence+transmission+of+sporadic+Creutzfeldt-Jakob+disease+creates+a+new+&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

snip...see full text ;

http://transmissiblespongiformencephalopathy.blogspot.com/2011/01/agent-strain-variation-in-human-prion.html


Friday, January 17, 2014

Annual report of the Scientific Network on BSE-TSE EFSA, Question No EFSA-Q-2013-01004, approved on 11 December 2013

TECHNICAL REPORT

http://efsaopinionbseanimalprotein.blogspot.com/2014/01/annual-report-of-scientific-network-on.html


Sunday, January 19, 2014

National Prion Disease Pathology Surveillance Center Cases Examined1 as of January 8, 2014

http://prionunitusaupdate.blogspot.com/2014/01/national-prion-disease-pathology.html


Thursday, January 23, 2014

Medical Devices Containing Materials Derived from Animal Sources (Except for In Vitro Diagnostic Devices) [Docket No. FDA–2013–D–1574]

http://transmissiblespongiformencephalopathy.blogspot.com/2014/01/medical-devices-containing-materials.html


Wednesday, January 15, 2014

INFECTION PREVENTION AND CONTROL OF CJD, VCJD AND OTHER HUMAN PRION DISEASES IN HEALTHCARE AND COMMUNITY SETTINGS Variably Protease-Sensitive Prionopathy (VPSPr) January 15, 2014

http://transmissiblespongiformencephalopathy.blogspot.com/2014/01/infection-prevention-and-control-of-cjd.html


Sunday, August 11, 2013

Creutzfeldt-Jakob Disease CJD cases rising North America updated report August 2013

*** Creutzfeldt-Jakob Disease CJD cases rising North America with Canada seeing an extreme increase of 48% between 2008 and 2010

http://creutzfeldt-jakob-disease.blogspot.com/2013/08/creutzfeldt-jakob-disease-cjd-cases.html


Sunday, October 13, 2013

*** CJD TSE Prion Disease Cases in Texas by Year, 2003-2012

http://creutzfeldt-jakob-disease.blogspot.com/2013/10/cjd-tse-prion-disease-cases-in-texas-by.html


Saturday, November 16, 2013

Management of neurosurgical instruments and patients exposed to creutzfeldt-jakob disease 2013 December

Infect Control Hosp Epidemiol.

http://creutzfeldt-jakob-disease.blogspot.com/2013/11/management-of-neurosurgical-instruments.html


Monday, December 02, 2013

*** A parliamentary inquiry has been launched today into the safety of blood, tissue and organ screening following fears that vCJD – the human form of ‘mad cow’ disease – may be being spread by medical procedures

http://creutzfeldt-jakob-disease.blogspot.com/2013/12/a-parliamentary-inquiry-has-been.html


Wednesday, December 11, 2013

Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob Disease

http://creutzfeldt-jakob-disease.blogspot.com/2013/12/detection-of-infectivity-in-blood-of.html


wasted days and wasted nights...Freddy Fender

MOM DOD 12/14/97 confirm ‘hvCJD’ just made a promise to mom, NEVER FORGET! and never let them forget. ...

kind regards, terry

layperson

Terry S. Singeltary Sr. P.O. Box 42 Bacliff, Texas USA 77518 flounder9@verizon.net


Wednesday, January 29, 2014

Another Suspect case of Creutzfeldt-Jakob disease investigated in Brazil

http://creutzfeldt-jakob-disease.blogspot.com/2014/01/another-suspect-case-of-creutzfeldt.html


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