Friday, May 23, 2014
spoke with media spokesperson at LG Health, and said there was no official
report on their site, and didn’t think there would be. I ask if I should just
roll with the media reporting this, and he said that the Lancaster online was
o.k. by them...tss
silent carriers, sub-clinical, are risk factors for iCJD, for the potential
for friendly fire, pass it forward, or what the call iatrogenic CJD. in my
opinion, this is a great risk factor for CWD consumption/exposure from hunters
eating sub-clinical cwd infected cervid.
Rare disease at LGH
Rare disease that in one form is mad cow disease found
at Lancaster General Hospital
Posted: Friday, May 23, 2014 8:46 am | Updated: 9:35 am, Fri May 23, 2014.
By RYAN ROBINSON | Staff Writer
A rare disease that in one form is known as mad cow disease was discovered
at Lancaster General Hospital. A patient had Creutzfeldt-Jakob Disease (CJD),
according to John Lines, Lancaster General Health’s director of public
relations. The person was treated on May 15 in the trauma unit for injuries
unrelated to CJD and died from those injuries the following day.
Hospital staff learned the patient had the disease from his medical record
as he was being brought into the hospital, Lines said Friday.
CJD affects 1 in a million people and causes dementia, and eventually,
death.
Lines said he could not divulge any additional information about the
patient.
LGH notified the state department of health and the Centers for Disease
Control and Prevention the day the patient was brought into the hospital, Lines
said. The hospital also contacted the National Prion Disease Pathology
Surveillance Center.
That CDC-operated agency serves as a clearinghouse for CJD cases across the
country and provides guidance on patient care and recommended measures to ensure
the safety of clinical staff and other patients, Lines said. LGH followed those
measures.
Areas where the patient was were cleaned with a highly-concentrated bleach
solution for 30 minutes, Lines said.
All items used in the care of the patient that may have been exposed to
blood or bodily fluids were discarded and incinerated.
“It is important to note that CJD is not transmitted from human to human by
normal contact,” Lines said. “It is not airborne. There is no known
human-to-human transmission through blood exposure.”
CDC has been transmitted through brain or spinal cord surgery, but those
surgeries were not done in this case, Lines said.
Officials do not believe the patient had the form of CDC known as mad cow
disease, he said.
“Had the infection been caused by tainted meat, we would have expected to
have seen other cases,” Lines said. “That has not been the case.”
please see this old study, it pretty much says it all, and still amazes me
today ;
1: J Neurol Neurosurg Psychiatry 1994 Jun;57(6):757-8
*** Transmission of Creutzfeldt-Jakob disease to a chimpanzee by electrodes
contaminated during neurosurgery.
Gibbs CJ Jr, Asher DM, Kobrine A, Amyx HL, Sulima MP, Gajdusek DC.
Laboratory of Central Nervous System Studies, National Institute of
Neurological Disorders and Stroke, National Institutes of Health,
Bethesda, MD 20892....
*** Stereotactic multicontact electrodes used to probe the cerebral cortex
of a middle aged woman with progressive dementia were previously implicated in
the accidental transmission of Creutzfeldt-Jakob disease (CJD) to two younger
patients. The diagnoses of CJD have been confirmed for all three cases. More
than two years after their last use in humans, after three cleanings and
repeated sterilisation in ethanol and formaldehyde vapour, the electrodes were
implanted in the cortex of a chimpanzee. Eighteen months later the animal became
ill with CJD. This finding serves to re-emphasise the potential danger posed by
reuse of instruments contaminated with the agents of spongiform
encephalopathies, even after scrupulous attempts to clean them.
PMID: 8006664 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8006664&dopt=Abstract
*** our results raise the possibility that CJD cases classified as VV1 may
include cases caused by iatrogenic transmission of sCJD-MM1 prions or food-borne
infection by type 1 prions from animals, e.g., chronic wasting disease prions in
cervid. In fact, two CJD-VV1 patients who hunted deer or consumed venison have
been reported (40, 41). The results of the present study emphasize the need for
traceback studies and careful re-examination of the biochemical properties of
sCJD-VV1 prions. ***
Thursday, January 2, 2014
*** CWD TSE Prion in cervids to hTGmice, Heidenhain Variant
Creutzfeldt-Jacob Disease MM1 genotype, and iatrogenic CJD ??? ***
Sunday, April 06, 2014
SPORADIC CJD and the potential for zoonotic transmission there from, either
directly or indirectly via friendly fire iatrogenic mode, evidence to date
*** The potential impact of prion diseases on human health was greatly
magnified by the recognition that interspecies transfer of BSE to humans by beef
ingestion resulted in vCJD. While changes in animal feed constituents and
slaughter practices appear to have curtailed vCJD, there is concern that CWD of
free-ranging deer and elk in the U.S. might also cross the species barrier.
Thus, consuming venison could be a source of human prion disease. Whether BSE
and CWD represent interspecies scrapie transfer or are newly arisen prion
diseases is unknown. Therefore, the possibility of transmission of prion disease
through other food animals cannot be ruled out. There is evidence that vCJD can
be transmitted through blood transfusion. There is likely a pool of unknown size
of asymptomatic individuals infected with vCJD, and there may be asymptomatic
individuals infected with the CWD equivalent. These circumstances represent a
potential threat to blood, blood products, and plasma supplies.
Wednesday, December 11, 2013
*** Detection of Infectivity in Blood of Persons with Variant and *** Sporadic
Creutzfeldt-Jakob Disease ***
Sunday, April 06, 2014
SPORADIC CJD and the potential for zoonotic transmission there from, either
directly or indirectly via friendly fire iatrogenic mode, evidence to date
Friday, January 10, 2014
vpspr, sgss, sffi, TSE, an iatrogenic by-product of gss, ffi, familial type
prion disease, what it ??? ...
Monday, May 19, 2014
Variant CJD: 18 years of research and surveillance
Sunday, May 18, 2014
Chronic Wasting Disease CWD TSE PRION DISEASE and the transmission to other
species
Tuesday, April 01, 2014
Questions linger in U.S. CJD cases 2005, and still do in 2014
Saturday, November 16, 2013
Management of neurosurgical instruments and patients exposed to
creutzfeldt-jakob disease 2013 December
Infect Control Hosp Epidemiol.
Tuesday, May 28, 2013
Late-in-life surgery associated with Creutzfeldt-Jakob disease: a
methodological outline for evidence-based guidance
Wednesday, January 15, 2014
*** INFECTION PREVENTION AND CONTROL OF CJD, VCJD AND OTHER HUMAN PRION
DISEASES IN HEALTHCARE AND COMMUNITY SETTINGS Variably Protease-Sensitive
Prionopathy (VPSPr) January 15, 2014
Wednesday, November 27, 2013
NHS failed to sterilise surgical instruments contaminated with 'mad cow'
disease
Friday, January 10, 2014
*** vpspr, sgss, sffi, TSE, an iatrogenic by-product of gss, ffi, familial
type prion disease, what it ???
Thursday, January 23, 2014
Medical Devices Containing Materials Derived from Animal Sources (Except
for In Vitro Diagnostic Devices) [Docket No. FDA–2013–D–1574]
Sunday, April 06, 2014
SPORADIC CJD and the potential for zoonotic transmission there from, either
directly or indirectly via friendly fire iatrogenic mode, evidence to date
“Cases of vCJD peaked in 2000, leading some scientists to speculate that
the disease has an incubation period of about a decade. Yet studies of different
forms of CJD suggest that the incubation time of vCJD could be much longer,
indicating that many people in Britain could be carrying the infection without
symptoms.”
Monday, October 14, 2013
Researchers estimate one in 2,000 people in the UK carry variant CJD
proteins
However, I think that the specific confusion there is that people talk
about sporadic CJD occurring at 1 per million. That is not your individual risk.
Your risk is 1 per million every year. Actually, it is nearer 2 per million per
year of the population will develop sporadic CJD, but your lifetime risk of
developing sporadic CJD is about 1 in 30,000. So that has not really changed.
When people talk about 1 per million, often they interpret that as thinking it
is incredibly rare. They think they have a 1-in-a-million chance of developing
this disease. You haven’t. You’ve got about a 1-in-30,000 chance of developing
it.
Cases of vCJD peaked in 2000, leading some scientists to speculate that the
disease has an incubation period of about a decade. Yet studies of different
forms of CJD suggest that the incubation time of vCJD could be much longer,
indicating that many people in Britain could be carrying the infection without
symptoms.
Tuesday, April 01, 2014
Questions linger in U.S. CJD cases 2005, and still do in 2014
Monday, March 10, 2014
Investigators study silent variant of mad cow disease Galveston Daily News
March 4, 2014
Wednesday, April 02, 2014
Distinct origins of dura mater graft-associated Creutzfeldt-Jakob disease:
past and future problems
Thursday, April 12, 2012
Health professions and risk of sporadic Creutzfeldt–Jakob disease, 1965 to
2010
Eurosurveillance, Volume 17, Issue 15, 12 April 2012
Research articles
Tuesday, May 28, 2013
Late-in-life surgery associated with Creutzfeldt-Jakob disease: a
methodological outline for evidence-based guidance
Sunday, June 9, 2013
TSEAC March 14, 2013: Transmissible Spongiform Encephalopathies Advisory
Committee Meeting Webcast
Tuesday, May 21, 2013
CJD, TSE, PRION, BLOOD Abstracts of the 23rd Regional Congress of the
International Society of Blood Transfusion, Amsterdam, The Netherlands, June
2-5, 2013
Tuesday, March 5, 2013
Use of Materials Derived From Cattle in Human Food and Cosmetics; Reopening
of the Comment Period FDA-2004-N-0188-0051 (TSS SUBMISSION)
FDA believes current regulation protects the public from BSE but reopens
comment period due to new studies
Thursday, October 25, 2012
Current limitations about the cleaning of luminal endoscopes and TSE prion
risk factors there from
Article in Press
Saturday, January 16, 2010
Evidence For CJD TSE Transmission Via Endoscopes 1-24-3 re-Singeltary to
Bramble et al
Evidence For CJD/TSE Transmission Via Endoscopes
From Terry S. Singletary, Sr flounder@wt.net 1-24-3
Terry S. Singeltary Sr., P.O. BOX 42, Bacliff, Texas 77518 USA
Professor Michael Farthing wrote:
Louise Send this to Bramble (author) for a comment before we post. Michael
Tuesday, July 31, 2012
11 patients may have been exposed to fatal disease Creutzfeldt-Jakob
Disease CJD Greenville Memorial Hospital
Thursday, August 02, 2012
CJD case in Saint John prompts letter to patients Canada CJD case in Saint
John prompts letter to patients
Saturday, February 12, 2011
Another Pathologists dies from CJD, another potential occupational death ?
another happenstance of bad luck, a spontaneous event from nothing, or
friendly fire ???
Thursday, July 08, 2010
GLOBAL CLUSTERS OF CREUTZFELDT JAKOB DISEASE - A REVIEW 2010
Sunday, May 10, 2009
Meeting of the Transmissible Spongiform Encephalopathies Committee On June
12, 2009 (Singeltary submission)
Thursday, January 29, 2009
Medical Procedures and Risk for Sporadic Creutzfeldt-Jakob Disease, Japan,
1999-2008 (WARNING TO Neurosurgeons and Ophthalmologists) Volume 15, Number
2-February 2009 Research
Wednesday, August 20, 2008
Tonometer disinfection practice in the United Kingdom: A national survey
Tuesday, August 12, 2008
Biosafety in Microbiological and Biomedical Laboratories Fifth Edition 2007
(occupational exposure to prion diseases)
Monday, December 31, 2007
Risk Assessment of Transmission of Sporadic Creutzfeldt-Jakob Disease in
Endodontic Practice in Absence of Adequate Prion Inactivation
Subject: CJD: update for dental staff
Date: November 12, 2006 at 3:25 pm PST
1: Dent Update. 2006 Oct;33(8):454-6, 458-60.
CJD: update for dental staff.
Friday, July 19, 2013
Beaumont Hospital in Dublin assessing patients for CJD
Saturday, September 21, 2013
CJD CONFIRMED in patient at New Hampshire Department of Health and Human
Services (DHHS), Catholic Medical Center (CMC), and the Manchester Health
Department (MHD)
Thursday, September 26, 2013
Minimise transmission risk of CJD and vCJD in healthcare settings Guidance
Wednesday, June 19, 2013
Spreading of tau pathology in Alzheimer's disease by cell-to-cell
transmission
MAD COW TESTING ONLY CATCHES SOME MAD COWS
SPREADING IT ALL AROUND
Saturday, October 19, 2013
***A comparative study of modified confirmatory techniques and additional
immuno-based methods for non-conclusive autolytic Bovine spongiform
encephalopathy cases
Sunday, October 27, 2013
A Kiss of a Prion: New Implications for Oral Transmissibility
Wednesday, December 11, 2013
*** Detection of Infectivity in Blood of Persons with Variant and Sporadic
Creutzfeldt-Jakob Disease ***
Sunday, January 19, 2014
*** National Prion Disease Pathology Surveillance Center Cases Examined1 as
of January 8, 2014 ***
Saturday, April 19, 2014
Exploring the zoonotic potential of animal prion diseases: In vivo and in
vitro approaches
TSS
Saturday, April 19, 2014
Human prion diseases and the risk of their transmission during anatomical
dissection
kind regards, terry
layperson, MOM DOD 12/14/97 confirmed hvCJD, just made a promise to mom,
never forget, and never let them forget...tss
Terry S. Singeltary Sr.
Bacliff, Texas USA 77518
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