Monday, March 29, 2010

Irma Linda Andablo CJD Victim, she died at 38 years old on February 6, 2010 in Mesquite Texas

Irma Linda Andablo CJD Victim, she died at 38 years old on February 6, 2010 in Mesquite Texas.She left 6 Kids and a Husband.The Purpose of this web is to give information in Spanish to the Hispanic community, and to all the community who want's information about this terrible disease.-

Physician Discharge Summary, Parkland Hospital, Dallas Texas

Admit Date: 12/29/2009 Discharge Date: 1/20/2010 Attending Provider: Greenberg, Benjamin Morris; General Neurology Team: General Neurology Team

Linda was a Hispanic female with no past medical history presents with 14 months of incresing/progressive altered mental status, generalized weakness, inability to walk, loss of appetite, inability to speak, tremor and bowel/blader incontinence.She was, in her usual state of health up until February, 2009, when her husbans notes that she began forgetting things like names and short term memories. He also noticed mild/vague personality changes such as increased aggression. In March, she was involved in a hit and run MVA,although she was not injured. The police tracked her down and ticketed her. At that time, her son deployed to Iraq with the Army and her husband assumed her mentation changes were due to stress over these two events. Also in March, she began to have weakness in her legs, making it difficult to walk. Over the next few months, her mentation and personality changes worsened, getting to a point where she could no longer recognized her children. She was eating less and less. She was losing more weight. In the last 2-3 months, she reached the point where she could not walk without an assist, then 1 month ago, she stopped talking, only making grunting/aggressive sounds when anyone came near her. She also became both bowel and bladder incontinent, having to wear diapers. Her '"tremor'" and body jerks worsened and her hands assumed a sort of permanent grip position, leading her family to put tennis balls in her hands to protect her fingers.

The husband says that they have lived in Nebraska for the past 21 years. They had seen a doctor there during the summer time who prescribed her Seroquel and Lexapro, Thinking these were sx of a mood disorder. However, the medications did not help and she continued to deteriorate clinically. Up until about 6 years ago, the pt worked at Tyson foods where she worked on the assembly line, slaughtering cattle and preparing them for packaging. She was exposed to brain and spinal cord matter when she would euthanize the cattle. The husband says that he does not know any fellow workers with a similar illness. He also says that she did not have any preceeding illness or travel.

http://www.recordandoalinda.com/index.php?option=com_content&view=article&id=19:cjd-english-info&catid=9:cjd-ingles&Itemid=8


Irma Linda Andablo, victima de CJD

"...padeció durante un año de CJD Esporádico, Falleció a la edad de 38 años en la ciudad de Mesquite Texas un 6 de Febrero del año 2010" Irma Linda Martinez nació en el pueblo de Batesville Texas un 17 de mayo de 1971, padeció durante un año de CJD Esporádico (mal de la vaca loca conocido en español) Falleció a la edad de 38 años en la ciudad de Mesquite Texas un 6 de Febrero del año 2010. A continuación describiremos datos de su padecimiento: Se casó a la edad de 16 años con Everardo Andablo (Lalo) ella residió en Lexington Nebraska, desde ese entonces, trabajó aproximadamente 11 años en una compañia de matanza de vacas y procesadora de carne (Tyson) ella trabajaba en el rastro o el área de matanza, para el 2008 ella trabajaba como agente de seguridad para esta misma compañia, para ese entonces ella empezó a presentar cambios en su vida, su próximo trabajo fue en Subway dentro de una tienda comercial, donde los cambios de salud empezaron a ser muy notorios pues empezó a perder mucho peso, de 237 L de su peso normal empezó perdiendo 24 L en menos de un mes, esto era sorprendente!!! fué entonces cuando dejó el trabajo en febrero del 2009, de repente empezó a olvidar datos importantes. La siguiente información es una traducción pertenece al comunicado que el equipo de neurologia del hospital Parkland en la ciudad de Dallas Texas liberó a su salida, después de haber estado internada del 29 de diciembre del 2009 a enero 20 del 2010, en este comunicado se encuentra el historial tanto médico como de sintomas presentados en Linda: Physician Discharge Summary : (traducido y adaptado) "...Mujer de 38 años presento 10 meses de una estado mental progresivo y alterado, con debilidad general, temblor, inhabilidad para caminar, para hablar, con pérdida de apetito e incontinencia de esfínteres, ella empezó a mostrar debilidad en las piernas, durante los siguientes meses su estado mental se agravó al tanto que ella no conoció más a sus propios hijos" "El 29 de Diciembre del 2009 Fué admitida en el Hospital Parkland de Dallas por demencia de acuerdo a los síntomas de presentaba, Mujer de 38 años presentó 14 meses de una estado mental progresivo y alterado, con debilidad general, temblor, inhabilidad para caminar, para hablar, con pérdida de apetito e incontinencia de esfinteres. Ella empezó a olvidar los nombres de las personas que la rodeaban, datos importantes personales, también presentó algunos cambios de personalidad como incremento de agresión.Para el mes de Marzo del 2008 ella empezó a mostrar debilidad en las piernas, durante los siguientes meses su estado mental se agravó al tanto que ella no conoció más a sus propios hijos (6 hijos), ella cada vez comia menos, cada vez perdia más peso.Para el tiempo que ella arrivo a Dallas para la navidad del 2009 ella no caminaba en lo absoluto, no hablaba solo hacia sonidos agresivos cuando alguien se acercaba a ella, el temblor en sus manos empezó a ser más fuerte, sus manos solo tenian posición de sostener algo fuerte, ella siempre... Read more...

http://www.recordandoalinda.com/


"...padeció durante un año de CJD Esporádico, Falleció a la edad de 38 años en la ciudad de Mesquite Texas un 6 de Febrero del año 2010"

Irma Linda Martinez nació en el pueblo de Batesville Texas un 17 de mayo de 1971, padeció durante un año de CJD Esporádico (mal de la vaca loca conocido en español) Falleció a la edad de 38 años en la ciudad de Mesquite Texas un 6 de Febrero del año 2010.

A continuación describiremos datos de su padecimiento:

Se casó a la edad de 16 años con Everardo Andablo (Lalo) ella residió en Lexington Nebraska, desde ese entonces, trabajó aproximadamente 11 años en una compañia de matanza de vacas y procesadora de carne (Tyson) ella trabajaba en el rastro o el área de matanza, para el 2008 ella trabajaba como agente de seguridad para esta misma compañia, para ese entonces ella empezó a presentar cambios en su vida, su próximo trabajo fue en Subway dentro de una tienda comercial, donde los cambios de salud empezaron a ser muy notorios pues empezó a perder mucho peso, de 237 L de su peso normal empezó perdiendo 24 L en menos de un mes, esto era sorprendente!!! fué entonces cuando dejó el trabajo en febrero del 2009, de repente empezó a olvidar datos importantes.

La siguiente información es una traducción pertenece al comunicado que el equipo de neurologia del hospital Parkland en la ciudad de Dallas Texas liberó a su salida, después de haber estado internada del 29 de diciembre del 2009 a enero 20 del 2010, en este comunicado se encuentra el historial tanto médico como de sintomas presentados en Linda:

Physician Discharge Summary : (traducido y adaptado)

"...Mujer de 38 años presento 10 meses de una estado mental progresivo y alterado, con debilidad general, temblor, inhabilidad para caminar, para hablar, con pérdida de apetito e incontinencia de esfínteres, ella empezó a mostrar debilidad en las piernas, durante los siguientes meses su estado mental se agravó al tanto que ella no conoció más a sus propios hijos"

"El 29 de Diciembre del 2009 Fué admitida en el Hospital Parkland de Dallas por demencia de acuerdo a los síntomas de presentaba, Mujer de 38 años presentó 14 meses de una estado mental progresivo y alterado, con debilidad general, temblor, inhabilidad para caminar, para hablar, con pérdida de apetito e incontinencia de esfinteres. Ella empezó a olvidar los nombres de las personas que la rodeaban, datos importantes personales, también presentó algunos cambios de personalidad como incremento de agresión.Para el mes de Marzo del 2008 ella empezó a mostrar debilidad en las piernas, durante los siguientes meses su estado mental se agravó al tanto que ella no conoció más a sus propios hijos (6 hijos), ella cada vez comia menos, cada vez perdia más peso.Para el tiempo que ella arrivo a Dallas para la navidad del 2009 ella no caminaba en lo absoluto, no hablaba solo hacia sonidos agresivos cuando alguien se acercaba a ella, el temblor en sus manos empezó a ser más fuerte, sus manos solo tenian posición de sostener algo fuerte, ella siempre portaba pelotas pequeñas para que no se lastimara con sus propias uñas"

En terminos Médicos ella prensento un desorden mental con ansiedad y pérdida del habla y contracciones en los musculos que la inmobilizaba. Esto llevo a los médicos a predecir el diagnostico de CJD esporádico o variante, después de reuniones familiares se llego al acuerdo de no proseguir con los exámenes indicados como una biopsia cerebral debido al estado de debilidad y gravedad de ella, pues peligraba su vida y por consiguiente peligraban los médicos que le aplicarian el exámen ya que es demasiado contagioso.

Ella fué dada de alta con el diagnostico de CJD Esporádico, sin medicamento y con pocas esperanzas y semanas de vida.

http://www.recordandoalinda.com/index.php?option=com_content&view=article&id=2:frontpage&catid=1:frontpage


Wednesday, February 24, 2010

Transmissible Spongiform encephalopathy (TSE) animal and human TSE in North America 14th

ICID International Scientific Exchange Brochure -

http://transmissiblespongiformencephalopathy.blogspot.com/2010/02/transmissible-spongiform-encephalopathy.html


TSE

http://transmissiblespongiformencephalopathy.blogspot.com/


Sunday, March 28, 2010

Nor-98 atypical Scrapie, atypical BSE, spontaneous TSE, trade policy, sound science ?

http://nor-98.blogspot.com/2010/03/nor-98-atypical-scrapie-atypical-bse.html


Greetings !

IF you want to help our fine friends down under, please sign this petition, and maybe leave a short note as to why you are signing it. Trading regulations on different TSEs are now being dictated by junk science. the USA even has separate slaughtering facilities for over seas market, so more stringent protocol can take place on TSE safety, but yet here in the USA, we get the slop. why should this be this way. all this could be alleviated if they would just TEST, TEST, TEST. what do they fear by testing ? all the USA is doing now is what the U.K. did when they traded their strain of BSE around the globe. now by the BSE MRR policy, this is legal now. IF USA scrapie transmitted to USA bovine DOES NOT FEATURE U.K. C-BSE PATHOLOGY, THEN WHY WOULD HUMAN TSE THERE FROM LOOK LIKE U.K. NVCJD ? let's stand together and go back to the BSE GBR risk assessments, even better the GBR system to include all TSE, and abolish the BSE MRR policy. THE BSE MRR policy is nothing more than a legal tool to trade all strains of TSE globally. IT's as if the U.K. BSE nvCJD blunder did not even happen with these folks for trade. TSE may be a long incubating disease, but it's a disease that once clinical, it is a 100% fatal. we must stop this. you can help...

kind regards, terry

Australians Reject Beef Imports From BSE (Mad Cow) Affected Countries 10 Signatures

Published by Vida Thomson on Mar 29, 2010 Category: National AffairsRegion: AustraliaTarget: Australian GovernmentWeb site: http://www.facebook.com/?sk=messages&tid=139764794... Background (Preamble): On 1st March 2010, the Australian Government lifted the ban on Beef imports from countries which are affected by BSE (Bovine Spongiform Encephalopathy or Mad Cow Disease). On 8th March, an Import Risk Assessment Analysis (IRAA) was announced in response to public outcry and a lack of supporting scientific consideration.

The IRAA could take up to 2 years to complete and will only focus on implications for animal - not human - health. Petition: We, the undersigned, resolutely and absolutely reject the Australian Government's intention to accept beef from countries affected by BSE (Mad Cow Disease), into Australia. We reject the Import Risk Analysis as this will not safeguard against BSE and the resultant deaths from human variant vCJD.

Science cannot protect us from a range of TSEs (Transmissable Spongiform Encephalopathies) as there is NO definitive test which will accurately identify or exclude BSE in imported beef from BSE affected countries. Science relating to TSEs has not evolved sufficiently to allow this to be used as a method to support increasing Australia's risk to the horrific and devastating effects of BSE and vCJD.

We do not want imported beef! Our stand is to keep Australia BSE-free, protect the Australian beef industry and protect Australians from vCJD death. We say: NO IMPORTED BEEF from BSE affected countries! Sign the petitionThe Australians Reject Beef Imports From BSE (Mad Cow) Affected Countries petition to Australian Government was written by Vida Thomson and is hosted free of charge at GoPetition. Contact author here.

http://www.gopetition.com.au/online/35173.html


SEE SIGNATURES HERE ;

http://www.gopetition.com.au/online/35173/signatures.html




DEEP THROAT TO TSS 2000-2001 (take these old snips of emails with how ever many grains of salt you wish. ...tss)

The most frightening thing I have read all day is the report of Gambetti's finding of a new strain of sporadic cjd in young people...Dear God, what in the name of all that is holy is that!!! If the US has different strains of scrapie.....why????than the UK...then would the same mechanisms that make different strains of scrapie here make different strains of BSE...if the patterns are different in sheep and mice for scrapie.....could not the BSE be different in the cattle, in the mink, in the humans.......I really think the slides or tissues and everything from these young people with the new strain of sporadic cjd should be put up to be analyzed by many, many experts in cjd........bse.....scrapie Scrape the damn slide and put it into mice.....wait.....chop up the mouse brain and and spinal cord........put into some more mice.....dammit amplify the thing and start the damned research.....This is NOT rocket science...we need to use what we know and get off our butts and move....the whining about how long everything takes.....well it takes a whole lot longer if you whine for a year and then start the research!!! Not sure where I read this but it was a recent press release or something like that: I thought I would fall out of my chair when I read about how there was no worry about infectivity from a histopath slide or tissues because they are preserved in formic acid, or formalin or formaldehyde.....for God's sake........ Ask any pathologist in the UK what the brain tissues in the formalin looks like after a year.......it is a big fat sponge...the agent continues to eat the brain ......you can't make slides anymore because the agent has never stopped........and the old slides that are stained with Hemolysin and Eosin......they get holier and holier and degenerate and continue...what you looked at 6 months ago is not there........Gambetti better be photographing every damned thing he is looking at.....

Okay, you need to know. You don't need to pass it on as nothing will come of it and there is not a damned thing anyone can do about it. Don't even hint at it as it will be denied and laughed at.......... USDA is gonna do as little as possible until there is actually a human case in the USA of the nvcjd........if you want to move this thing along and shake the earth....then we gotta get the victims families to make sure whoever is doing the autopsy is credible, trustworthy, and a saint with the courage of Joan of Arc........I am not kidding!!!! so, unless we get a human death from EXACTLY the same form with EXACTLY the same histopath lesions as seen in the UK nvcjd........forget any action........it is ALL gonna be sporadic!!!

And, if there is a case.......there is gonna be every effort to link it to international travel, international food, etc. etc. etc. etc. etc. They will go so far as to find out if a sex partner had ever traveled to the UK/europe, etc. etc. .... It is gonna be a long, lonely, dangerous twisted journey to the truth. They have all the cards, all the money, and are willing to threaten and carry out those threats....and this may be their biggest downfall...

Thanks as always for your help. (Recently had a very startling revelation from a rather senior person in government here..........knocked me out of my chair........you must keep pushing. If I was a power person....I would be demanding that there be a least a million bovine tested as soon as possible and agressively seeking this disease. The big players are coming out of the woodwork as there is money to be made!!! In short: "FIRE AT WILL"!!! for the very dumb....who's "will"! "Will be the burden to bare if there is any coverup!"

again it was said years ago and it should be taken seriously....BSE will NEVER be found in the US! As for the BSE conference call...I think you did a great service to freedom of information and making some people feign integrity...I find it scary to see that most of the "experts" are employed by the federal government or are supported on the "teat" of federal funds. A scary picture! I hope there is a confidential panel organized by the new government to really investigate this thing.

You need to watch your back........but keep picking at them.......like a buzzard to the bone...you just may get to the truth!!! (You probably have more support than you know. Too many people are afraid to show you or let anyone else know. I have heard a few things myself... you ask the questions that everyone else is too afraid to ask.)

snip...end


CJD SURVEILLANCE TEXAS

http://cjdtexas.blogspot.com/2007/12/creutzfeldt-jakob-disease-surveillance.html




2009 UPDATE ON ALABAMA AND TEXAS MAD COWS 2005 and 2006


http://bse-atypical.blogspot.com/2006/08/bse-atypical-texas-and-alabama-update.html



CJD USA RISING, with UNKNOWN PHENOTYPE ;

5 Includes 41 cases in which the diagnosis is pending, and 17 inconclusive cases; 6 Includes 46 cases with type determination pending in which the diagnosis of vCJD has been excluded.


http://www.cjdsurveillance.com/pdf/case-table.pdf




Saturday, January 2, 2010

Human Prion Diseases in the United States January 1, 2010 ***FINAL***



http://prionunitusaupdate2008.blogspot.com/2010/01/human-prion-diseases-in-united-states.html




Terry S. Singeltary Sr. P.O. Box 42 Bacliff, Texas USA 77518

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Sunday, March 28, 2010

SPAIN BSE, Nor-98 atypical scrapie, SPORADIC CJD HIGH INCIDENT RATE >2 PER MILLION

Numero de focos de Encefalopatia Espongiforme Bovine en Espana 2009 - 1010


2009 = 18 cases BSE

http://www.eeb.es/pags/2009.htm


2010 to date = 4 cases of BSE

http://www.eeb.es/pags/espana.htm#2010


BSE SPAIN

Año 2000

http://www.eeb.es/pags/2000.htm


Año 2001

http://www.eeb.es/pags/2000.htm#2001


Año 2002

http://www.eeb.es/pags/2002.htm


Año 2003

http://www.eeb.es/pags/2003.htm


Año 2004

http://www.eeb.es/pags/2004.htm


Año 2005

http://www.eeb.es/pags/2005.htm


Año 2006

http://www.eeb.es/pags/2006.htm


Año 2007

http://www.eeb.es/pags/2007.htm


Año 2008

http://www.eeb.es/pags/2008.htm


Año 2009

http://www.eeb.es/pags/2009.htm


BSE SPAIN 2010 Situacion en Espana Total casos

http://www.eeb.es/pags/espana.htm#2010



Greetings,

PLEASE NOTE HIGH INCIDENT OF SPORADIC CJD AND BSE IN THE ALAVA, VIZCAYA, AND GUIPUZCOA AREAS ? another coincident, or BSE related. remember, BSE will propagate as nvCJD and or sporadic CJD in humanized transgenic mice, and please NOTE ALSO, the close proximity of BASQUE COUNTRY SPAIN TO ALAVA, VIZCAYA, AND GUIPUZCOA AREAS ? SO, you have a high rate of sporadic CJD cases in an area of BSE and Nor-98 atypical scrapie cases, another spontaneous coincidence, or a related event ?


NOTE THE SPORADIC CJD INCIDENT RATE AT > 2 CASES PER MILLION ;


SEE CJD UPDATE 2010

SEE PAGE 4 ;

Notificaciones* al RNEETH (1993-febrero 2010)

• Por año diagnóstico. Existe 1 caso más sin año diagnóstico

AÑO

CCAA 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 TOTAL

Andalucia 4 6 2 2 5 4 8 11 16 14 9 11 16 15 13 19 11 1 167

Aragon 0 0 1 0 5 4 1 3 4 0 2 0 5 2 2 5 4 1 39

Asturias 2 0 2 0 1 2 3 2 2 0 5 2 1 0 0 0 0 0 22

Baleares 1 2 0 1 1 0 2 0 1 1 1 3 1 0 0 1 4 0 19

Canarias 0 0 0 0 4 4 4 2 2 2 2 2 2 3 3 1 3 0 34

Cantabria 1 2 0 0 2 4 3 3 0 2 0 0 1 0 0 2 0 0 20

Castilla la Mancha 0 1 1 2 2 1 2 2 1 2 0 2 5 3 5 6 7 0 42

Castilla-Leon 2 1 6 2 7 4 4 6 8 5 6 6 7 7 7 12 5 0 95

Cataluna 8 6 3 6 6 15 16 9 13 11 7 19 15 16 13 14 7 0 184

Valencia 1 3 3 7 5 12 11 10 12 13 17 10 8 8 19 16 9 2 166

Extremadura 0 0 0 1 1 2 2 0 0 3 1 0 2 7 5 3 1 0 28

Galicia 1 1 3 0 0 11 3 5 8 7 1 7 6 5 3 2 0 0 63

Madrid 4 4 5 7 5 7 9 10 16 7 12 8 13 16 8 8 13 0 152

Murcia 1 0 0 0 1 0 1 0 2 3 2 2 3 1 6 2 3 0 27

Navarra 1 0 0 2 1 0 2 2 1 0 0 0 4 2 0 0 0 0 15

Pais Vasco 2 3 1 6 4 8 5 8 8 9 7 6 11 10 11 8 4 1 112

La Rioja 2 0 0 0 1 1 0 0 1 0 1 0 1 0 1 0 0 0 8

TOTAL 30 29 27 36 51 79 76 73 95 79 73 78 101 95 96 99 71 5 1193

• Por año diagnóstico. Existe 1 caso más sin año diagnóstico

REGISTRO ESPAÑOL DE EETH

1993-febrero 2010

ECJ = 957

vECJ = 5

IFL = 44

GSS = 2

Esporadico = 905

Familiar = 46

Yatrogenico = 6

* Existen 2 casos mas con diagnóstico pendiente de clasificación

ALSO, ON PAGE 14, NOTE THE HIGH INCIDENCE IN THIS SAME AREA ;

Número de casos de Insomnio Familiar Letal por CA. 1993-febrero 2010

HIGH INCIENCE RATE AT 18 CASES


please see full text ;


REGISTRO NACIONAL DE ENCEFALOPATÍAS ESPONGIFORMES TRANSMISIBLES HUMANAS C.N.E y Servicios de Vigilancia Epidemiológica de CCAA (Situación a 15 de febrero de 2010)


http://www.isciii.es/htdocs/pdf/DatosRegistroCreutzfeldJacob2.pdf



The EMBO Journal (2002) 21, 6358 - 6366 doi:10.1093/emboj/cdf653

BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein

Emmanuel A. Asante1, Jacqueline M. Linehan1, Melanie Desbruslais1, Susan Joiner1, Ian Gowland1, Andrew L. Wood1, Julie Welch1, Andrew F. Hill1, Sarah E. Lloyd1, Jonathan D.F. Wadsworth1 and John Collinge1

1.MRC Prion Unit and Department of Neurodegenerative Disease, Institute of Neurology, University College, Queen Square, London WC1N 3BG, UK Correspondence to:

John Collinge, E-mail: j.collinge@prion.ucl.ac.uk

Received 1 August 2002; Accepted 17 October 2002; Revised 24 September 2002


--------------------------------------------------------------------------------


Abstract

Variant Creutzfeldt–Jakob disease (vCJD) has been recognized to date only in individuals homozygous for methionine at PRNP codon 129. Here we show that transgenic mice expressing human PrP methionine 129, inoculated with either bovine spongiform encephalopathy (BSE) or variant CJD prions, may develop the neuropathological and molecular phenotype of vCJD, consistent with these diseases being caused by the same prion strain. Surprisingly, however, BSE transmission to these transgenic mice, in addition to producing a vCJD-like phenotype, can also result in a distinct molecular phenotype that is indistinguishable from that of sporadic CJD with PrPSc type 2. These data suggest that more than one BSE-derived prion strain might infect humans; it is therefore possible that some patients with a phenotype consistent with sporadic CJD may have a disease arising from BSE exposure.

Keywords:BSE, Creutzfeldt–Jakob disease, prion, transgenic


http://www.nature.com/emboj/journal/v21/n23/abs/7594869a.html


Monday, May 19, 2008

SPORADIC CJD IN FARMERS, FARMERS WIVES, FROM FARMS WITH BSE HERD AND ABATTOIRS

http://bseinquiry.blogspot.com/


Sunday, August 10, 2008

A New Prionopathy OR more of the same old BSe and sporadic CJD

http://creutzfeldt-jakob-disease.blogspot.com/2008/08/new-prionopathy-or-more-of-same-old-bse.html


Atypical/Nor98 scrapie in the Basque Country: a case report of eight outbreaks

BMC Veterinary Research 2010, 6:17 doi:10.1186/1746-6148-6-17

http://www.biomedcentral.com/content/pdf/1746-6148-6-17.pdf


Sunday, March 28, 2010

Atypical/Nor98 scrapie in the Basque Country: a case report of eight outbreaks

http://nor-98.blogspot.com/2010/03/atypicalnor98-scrapie-in-basque-country.html


Wednesday, March 3, 2010

NOR-98 ATYPICAL SCRAPIE USA 4 CASES DETECTED JANUARY 2010

Greetings,

Unusual event if you consider the officials hypothisis that Nor-98 atypical scrapie is a spontaneous event. seems there was a great deal of spontaneous mutations for this time period ;-)...TSS

http://nor-98.blogspot.com/2010/03/nor-98-atypical-scrapie-usa-4-cases.html


Thursday, March 11, 2010

CANADA TYPICAL AND ATYPICAL SCRAPIE REPORT TO MARCH 2010

http://nor-98.blogspot.com/2010/03/canada-typical-and-atypical-scrapie.html


Monday, November 30, 2009

USDA AND OIE COLLABORATE TO EXCLUDE ATYPICAL SCRAPIE NOR-98 ANIMAL HEALTH CODE

http://nor-98.blogspot.com/2009/11/usda-and-oie-collaborate-to-exclude.html


Monday, December 14, 2009

Similarities between Forms of Sheep Scrapie and Creutzfeldt-Jakob Disease Are Encoded by Distinct Prion Types

hmmm, this is getting interesting now...

Sporadic CJD type 1 and atypical/ Nor98 scrapie are characterized by fine (reticular) deposits,

see also ;

All of the Heidenhain variants were of the methionine/ methionine type 1 molecular subtype.

http://cjdusa.blogspot.com/2009/09/co-existence-of-scrapie-prion-protein.html


see full text ;

Monday, December 14, 2009

Similarities between Forms of Sheep Scrapie and Creutzfeldt-Jakob Disease Are Encoded by Distinct Prion Types

http://nor-98.blogspot.com/2009/12/similarities-between-forms-of-sheep.html


TSS

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Tuesday, March 16, 2010

Transmissible Spongiform Encephalopathy Agents: Safe Working and the Prevention of Infection: Part 4 REVISED FEB. 2010

Sent: Monday, March 15, 2010 12:19 PM Subject: Transmissible Spongiform Encephalopathy Agents: Safe Working and the Prevention of Infection: Part 4 REVISED FEB. 2010

Transmissible Spongiform Encephalopathy Agents: Safe Working and the Prevention of Infection: Part 4

PART 4

Infection control of CJD, vCJD and other human prion diseases in healthcare and community settings Part 4 has been redrafted (February 2010) to clarify how best to manage patients in healthcare and community settings. A number of recent policy decisions have been incorporated into this guidance including:

Standard infection control precautions should be used to clear up spillages as quickly as possible of all material from patients with, or “at increased risk” of, CJD/vCJD in a healthcare setting. 10,000ppm rather than 20,000ppm sodium hypochlorite is recommended for practical purposes.

High or medium risk tissues from patients with, or “at increased risk” of, CJD or vCJD, should be incinerated, and low risk tissues or body fluids should follow normal clinical waste disposal.

Instruments used in high or medium risk procedures on patients with, or “at increased risk” of, CJD/vCJD can be quarantined and re-used exclusively on the same patient, subject to tracking of instruments throughout the decontamination cycle, and ensuring that under no circumstances should quarantined instrument sets be reprocessed for use on other patients unless the diagnosis of CJD or vCJD has been positively excluded.

Individuals who have been identified prior to high risk surgery as having received blood or blood components from 80 or more donors since January 1980 are now designated as “at increased risk” of vCJD and have been added to Table 4a.

The anterior eye has been reclassified as low risk with regards to tissue infectivity. In addition, updated information on other guidance, including dentistry, anaesthesia and intensive care, has been incorporated.

Published: 2 June 2003

Revised and updated: 25 February 2010

Transmissible Spongiform Encephalopathy Agents: Safe Working and the Prevention of Infection: Part 4

CONTENTS

Introduction

Other relevant guidance

Caring for patients with, or “at increased risk“ of, CJD or vCJD

Management arrangements for infection control

Tissue infectivity

Iatrogenic transmission

CJD

vCJD

Patient categorisation

Patients “at increased risk” of CJD or vCJD

Hospital care of patients

Taking samples and other invasive medical procedures

Spillages

Clinical waste

Childbirth

Bed linen

Occupational exposure

Surgical procedures and instrument management

Single use instruments

Handling of instruments that are not designated as single-use

Quarantining instruments

Decontamination of instruments

Storage of instruments for research purposes

Incineration of instruments

Complex instruments

Use of laser for tonsillectomy – smoke plumes

Anaesthesia and intensive care

Endoscopy

Ophthalmology

Community healthcare

Caring for symptomatic patients at home

Spillages

Published: 2 June 2003

Clinical waste

Revised and updated: 25 February 2010

Transmissible Spongiform Encephalopathy Agents: Safe Working and the Prevention of Infection: Part 4

Bed linen

Pregnancy

Dentistry

After death

Published: 2 June 2003

Revised and updated: 25 February 2010

Transmissible Spongiform Encephalopathy Agents: Safe Working and the Prevention of Infection: Part 4

Introduction

snip...

http://www.dh.gov.uk/prod_consum_dh/groups/dh_digitalassets/@dh/@ab/documents/digitalasset/dh_113959.pdf



Saturday, January 23, 2010

Experimental Verification of a Traceback Phenomenon in Prion Infection

http://creutzfeldt-jakob-disease.blogspot.com/2010/01/experimental-verification-of-traceback.html


Sunday, January 17, 2010

CJD Following up: Patients never contracted brain disorder UW Hospital patients

http://creutzfeldt-jakob-disease.blogspot.com/2010/01/cjd-following-up-patients-never.html


Sunday, January 17, 2010

Human tissue, recovered from a donor history indicated increased risk factors for Creutzfeldt-Jacob disease Lions Eye Bank

http://creutzfeldt-jakob-disease.blogspot.com/2010/01/human-tissue-recovered-from-donor.html


Saturday, January 16, 2010

Evidence For CJD TSE Transmission Via Endoscopes 1-24-3 re-Singeltary to Bramble et al

http://creutzfeldt-jakob-disease.blogspot.com/2010/01/evidence-for-cjd-tse-transmission-via.html


Thursday, January 28, 2010

Multiorgan Detection and Characterization of Protease-Resistant Prion Protein in a Case of Variant CJD Examined in the United States

http://creutzfeldt-jakob-disease.blogspot.com/2010/01/multiorgan-detection-and.html


Friday, January 22, 2010

nvCJD Clause 2 : Blood donations

http://vcjdtransfusion.blogspot.com/2010/01/nvcjd-clause-2-blood-donations.html


Friday, November 20, 2009

SaBTO Advisory Committee on the Safety of Blood, Tissues and Organs Summary of the Eighth Meeting, 27 October 2009

http://vcjdtransfusion.blogspot.com/2009/11/sabto-advisory-committee-on-safety-of.html


Sunday, May 10, 2009

Meeting of the Transmissible Spongiform Encephalopathies Committee On June 12, 2009 (Singeltary submission)

http://tseac.blogspot.com/2009/05/meeting-of-transmissible-spongiform.html


Monday, August 17, 2009

Transmissible Spongiform Encephalopathy Agents: Safe Working and the Prevention of Infection: Annex J,K, AND D Published: 2009

http://creutzfeldt-jakob-disease.blogspot.com/2009/08/transmissible-spongiform-encephalopathy.html


Friday, July 17, 2009

Revision to pre-surgical assessment of risk for vCJD in neurosurgery and eye surgery units Volume 3 No 28; 17 July 2009

http://creutzfeldt-jakob-disease.blogspot.com/2009/07/revision-to-pre-surgical-assessment-of.html


Tuesday, August 12, 2008

Biosafety in Microbiological and Biomedical Laboratories Fifth Edition 2007 (occupational exposure to prion diseases)

http://creutzfeldt-jakob-disease.blogspot.com/2008/08/biosafety-in-microbiological-and.html


14th ICID International Scientific Exchange Brochure -

Final Abstract Number: ISE.114

Session: International Scientific Exchange

Transmissible Spongiform encephalopathy (TSE) animal and human TSE in North America

update October 2009

T. Singeltary

Bacliff, TX, USA

Background:

An update on atypical BSE and other TSE in North America. Please remember, the typical U.K. c-BSE, the atypical l-BSE (BASE), and h-BSE have all been documented in North America, along with the typical scrapie's, and atypical Nor-98 Scrapie, and to date, 2 different strains of CWD, and also TME. All these TSE in different species have been rendered and fed to food producing animals for humans and animals in North America (TSE in cats and dogs ?), and that the trading of these TSEs via animals and products via the USA and Canada has been immense over the years, decades.

Methods:

12 years independent research of available data

Results:

I propose that the current diagnostic criteria for human TSEs only enhances and helps the spreading of human TSE from the continued belief of the UKBSEnvCJD only theory in 2009. With all the science to date refuting it, to continue to validate this old myth, will only spread this TSE agent through a multitude of potential routes and sources i.e. consumption, medical i.e., surgical, blood, dental, endoscopy, optical, nutritional supplements, cosmetics etc.

Conclusion:

I would like to submit a review of past CJD surveillance in the USA, and the urgent need to make all human TSE in the USA a reportable disease, in every state, of every age group, and to make this mandatory immediately without further delay. The ramifications of not doing so will only allow this agent to spread further in the medical, dental, surgical arena's. Restricting the reporting of CJD and or any human TSE is NOT scientific. Iatrogenic CJD knows NO age group, TSE knows no boundaries. I propose as with Aguzzi, Asante, Collinge, Caughey, Deslys, Dormont, Gibbs, Gajdusek, Ironside, Manuelidis, Marsh, et al and many more, that the world of TSE Transmissible Spongiform Encephalopathy is far from an exact science, but there is enough proven science to date that this myth should be put to rest once and for all, and that we move forward with a new classification for human and animal TSE that would properly identify the infected species, the source species, and then the route.

http://ww2.isid.org/Downloads/14th_ICID_ISE_Abstracts.pdf


International Society for Infectious Diseases Web: http://www.isid.org

Saturday, January 2, 2010

Human Prion Diseases in the United States January 1, 2010 ***FINAL***

http://prionunitusaupdate2008.blogspot.com/2010/01/human-prion-diseases-in-united-states.html


my comments to PLosone here ;

http://www.plosone.org/annotation/listThread.action?inReplyTo=info%3Adoi%2F10.1371%2Fannotation%2F04ce2b24-613d-46e6-9802-4131e2bfa6fd&root=info%3Adoi%2F10.1371%2Fannotation%2F04ce2b24-613d-46e6-9802-4131e2bfa6fd


Friday, February 05, 2010

New Variant Creutzfelt Jakob Disease case reports United States 2010 A Review

http://vcjd.blogspot.com/2010/02/new-variant-creutzfelt-jakob-disease.html


Sunday, February 14, 2010

[Docket No. FSIS-2006-0011] FSIS Harvard Risk Assessment of Bovine Spongiform Encephalopathy (BSE)

http://bseusa.blogspot.com/2010/02/docket-no-fsis-2006-0011-fsis-harvard.html


Wednesday, February 24, 2010

Transmissible Spongiform encephalopathy (TSE) animal and human TSE in North America 14th

ICID International Scientific Exchange Brochure -

http://transmissiblespongiformencephalopathy.blogspot.com/2010/02/transmissible-spongiform-encephalopathy.html


TSE

http://transmissiblespongiformencephalopathy.blogspot.com/


Friday, February 05, 2010

New Variant Creutzfelt Jakob Disease case reports United States 2010 A Review

http://vcjd.blogspot.com/2010/02/new-variant-creutzfelt-jakob-disease.html


TSS

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